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CAS 2897640-93-4

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  • PROTAC HER2 degrader-1
    Targetmol
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    PROTAC HER2 degrader-1

    CAS:
    PROTACHER2 degrader-1 is a highly selective HER2 PROTAC degrader with a DC50 of 69 nM and a Dmax of 96%. It effectively inhibits HER2-positive cell proliferation and tumor growth by inducing sustained HER2 degradation and strongly inhibiting downstream pathways (AKT and ERK). Additionally, PROTACHER2 degrader-1 can induce apoptosis in BT-474 cells and is useful for researching HER2-positive cancers.
    Formula:C49H55N11O7
    Color and Shape:Solid
    Molecular weight:910.03

    Ref: TM-T211553