CAS 2899209-55-1

JAB-2485

Formula: C₂₅H₂₈ClF₂N₅O₂

Synonyms:

• JAB-2485

JAB-2485

CAS: 2899209-55-1

JAB-2485 is a highly potent and selective inhibitor of Aurora kinase A (AURKA), boasting an IC 50 of 0.33 nM, and demonstrates approximately 1700-fold selectivity for AURKA over AURKB. It induces cell cycle arrest and apoptosis, making it a valuable compound for cancer research [1].

Formula: C₂₅H₂₈ClF₂N₅O₂

Molecular weight: 503.97

Ref: TM-T86753