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CAS 2901054-39-3

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  • HPK1-IN-56
    Targetmol
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    HPK1-IN-56

    CAS:
    <p>HPK1-IN-56 (Compound A29) is an HPK1 inhibitor with an IC50 of 2.70 nM. It inhibits downstream p-SLP76 in Jurkat T cells with an IC50 of 8.1 nM. Additionally, HPK1-IN-56 induces IL-2 production in human PBMCs. This compound exhibits anticancer properties, enhancing T cell cytotoxicity and the antitumor efficacy of anti-PD-1 antibodies.</p>
    Formula:C24H26N8O
    Color and Shape:Solid
    Molecular weight:442.516

    Ref: TM-T204758