AR antagonist 5, identified by its CAS number 2902679-53-0, is a chemical compound that functions as an androgen receptor antagonist. This class of compounds is primarily studied for its potential therapeutic applications in conditions such as prostate cancer and other androgen-dependent diseases. The characteristics of AR antagonist 5 include its ability to bind to androgen receptors, thereby inhibiting the action of androgens like testosterone and dihydrotestosterone. This inhibition can lead to a reduction in the growth of androgen-sensitive tissues. The compound is typically characterized by its specific molecular structure, which includes functional groups that facilitate its interaction with the androgen receptor. Additionally, AR antagonist 5 may exhibit varying degrees of selectivity and potency, influencing its efficacy and safety profile in biological systems. As with many pharmacological agents, understanding its pharmacokinetics, metabolism, and potential side effects is crucial for its development and application in clinical settings.

AR antagonist 5

2902679-53-0: AR antagonist 5, identified by its CAS number 2902679-53-0, is a chemical compound that functions as an androgen receptor antagonist. This class of compounds is primarily studied for its potential therapeutic applications in conditions such as prostate cancer and other androgen-dependent diseases. The characteristics of AR antagonist 5 include its ability to bind to androgen receptors, thereby inhibiting the action of androgens like testosterone and dihydrotestosterone. This inhibition can lead to a reduction in the growth of androgen-sensitive tissues. The compound is typically characterized by its specific molecular structure, which includes functional groups that facilitate its interaction with the androgen receptor. Additionally, AR antagonist 5 may exhibit varying degrees of selectivity and potency, influencing its efficacy and safety profile in biological systems. As with many pharmacological agents, understanding its pharmacokinetics, metabolism, and potential side effects is crucial for its development and application in clinical settings.

<p>Compound 30a, known as AR Antagonist 5, is a selective androgen receptor (AR) antagonist that demonstrates an IC 50 value of 134.8 nM. It exhibits favorable pharmacokinetic properties, characterized by high skin exposure and low plasma exposure [1].</p>

CAS 2902679-53-0

AR antagonist 5

AR antagonist 5

Ref: TM-T85717