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CAS 29110-47-2

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Guanfacine

Description:
Guanfacine is a medication primarily used to treat attention deficit hyperactivity disorder (ADHD) and hypertension. It is classified as an alpha-2 adrenergic agonist, which means it works by stimulating alpha-2 receptors in the brain, leading to decreased sympathetic outflow and reduced blood pressure. The chemical formula for guanfacine is C9H9ClN2, and it features a guanidine structure with a phenyl ring, contributing to its pharmacological properties. Guanfacine is typically administered in its hydrochloride salt form, enhancing its solubility and bioavailability. The substance is known for its sedative effects, which can be beneficial in managing ADHD symptoms, particularly in children. Common side effects may include drowsiness, dry mouth, and fatigue. Due to its mechanism of action, guanfacine can also lead to bradycardia and hypotension, necessitating careful monitoring during treatment. Overall, guanfacine is a valuable therapeutic agent in specific clinical settings, with a well-established profile for efficacy and safety when used appropriately.
Formula:C9H9Cl2N3O
InChI:InChI=1S/C9H9Cl2N3O/c10-6-2-1-3-7(11)5(6)4-8(15)14-9(12)13/h1-3H,4H2,(H4,12,13,14,15)
InChI key:InChIKey=INJOMKTZOLKMBF-UHFFFAOYSA-N
SMILES:C(C(NC(=N)N)=O)C1=C(Cl)C=CC=C1Cl
Synonyms:
  • Acetamide, N-amidino-2-(2,6-dichlorophenyl)-
  • Guanfacin
  • Guanfacina
  • Guanfacine
  • Guanfascine
  • Guarfacine
  • N-(Aminoiminomethyl)-2,6-dichlorobenzeneacetamide
  • N-Amidino-2-(2,6-dichlorophenyl)acetamide
  • [(2,6-Dichlorophenyl)acetyl]guanidine
  • Benzeneacetamide, N-(aminoiminomethyl)-2,6-dichloro-
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Found 5 products.