CAS 29110-48-3
:Guanfacine hydrochloride
Description:
Guanfacine hydrochloride is a medication primarily used to treat attention deficit hyperactivity disorder (ADHD) and hypertension. It is an alpha-2 adrenergic agonist, which means it works by stimulating alpha-2 receptors in the brain, leading to decreased sympathetic outflow and reduced blood pressure. The substance appears as a white to off-white crystalline powder and is soluble in water, making it suitable for oral administration. Its chemical formula is C9H9ClN2, and it has a molecular weight of approximately 182.63 g/mol. Guanfacine hydrochloride is known for its sedative effects, which can be beneficial in managing ADHD symptoms by promoting calmness and focus. The drug is typically administered in tablet form, with dosing adjusted based on individual patient response and tolerability. Common side effects may include drowsiness, dry mouth, and fatigue. As with any medication, it is essential to use guanfacine hydrochloride under the guidance of a healthcare professional to ensure safety and efficacy.
Formula:C9H10Cl3N3O
InChI:InChI=1/C9H9Cl2N3O.ClH/c10-6-2-1-3-7(11)5(6)4-8(15)14-9(12)13;/h1-3H,4H2,(H4,12,13,14,15);1H
InChI key:InChIKey=DGFYECXYGUIODH-UHFFFAOYSA-N
SMILES:C(C(NC(=N)N)=O)C1=C(Cl)C=CC=C1Cl.Cl
Synonyms:- 2,6-Dichlorophenylacetylguanidine hydrochloride
- Benzeneacetamide, N-(aminoiminomethyl)-2,6-dichloro-, hydrochloride (1:1)
- Benzeneacetamide, N-(aminoiminomethyl)-2,6-dichloro-, monohydrochloride
- Bs 100-141
- Estulic
- Guanfacine HCl
- Guanfacine hydrochloride [USAN:JAN]
- Intuniv
- Lon 798
- N-(Aminoiminomethyl)-2,6-dichlorobenzeneacetamide hydrochloride
- N-(Aminoiminomethyl)-2,6-dichlorophenylacetamide monohydrochloride
- N-Amidino-2-(2,6-dichlorophenyl)acetamide hydrochloride
- N-Amidino-2-(2,6-dichlorophenyl)acetamide monohydrochloride
- Spd 503
- Tenex
- Tenex (pharmaceutical)
- Unii-Pml56A160O
- [(2,6-Dichlorophenyl)acetyl]guanidine monohydrochloride
- n-(aminoiminomethyl)-2,6-dichlorobenzeneacetamidehydrochloride
- [(2,6-DICHLOROPHENYL)ACETYL]GUANIDINE HYDROCHLORIDE
- N (AMINOIMINOMETHYL)-2,6-DICHLOROBENZENEACETAMIDE HYDROCHLORIDE SALT
- Guarfacine
- Guanfascine
- GUANFACINE HYDROCHLORIDE
- GUANFACIN HYDROCHLORIDE
- n-(aminoiminomethyl)-2,6-dichloro-benzeneacetamidmonohydrochloride
- n-amidino-2-(2,6-dichlorophenyl)acetamidehydrochloride
- bs100-141
- lon798
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Found 11 products.
Guanfacine Hydrochloride
CAS:Formula:C9H9Cl2N3O·HClPurity:>98.0%(T)(HPLC)Color and Shape:White to Almost white powder to crystalMolecular weight:282.55Guanfacine Hydrochloride
CAS:Aromatic imines and their derivatives, salts thereofFormula:C9H9Cl2N3O·HCIColor and Shape:White Off-White Crystalline PowderMolecular weight:384.92456Benzeneacetamide, N-(aminoiminomethyl)-2,6-dichloro-, hydrochloride (1:1)
CAS:Formula:C9H10Cl3N3OPurity:99%Color and Shape:SolidMolecular weight:282.5542N-Carbamimidoyl-2-(2,6-Dichlorophenyl)Acetamide Hydrochloride
CAS:N-Carbamimidoyl-2-(2,6-Dichlorophenyl)Acetamide HydrochloridePurity:99%Molecular weight:282.55g/molGuanfacine HCl
CAS:Formula:C9H9Cl2N3O·HClColor and Shape:Off-White SolidMolecular weight:246.09 36.46Guanfacine hydrochloride
CAS:Guanfacine hydrochloride (Intuniv) is a centrally acting antihypertensive agent with specificity towards ADRENERGIC ALPHA-2 RECEPTORS.Formula:C9H10Cl3N3OPurity:99.89% - 99.91%Color and Shape:SolidMolecular weight:282.55Guanfacine hydrochloride
CAS:Formula:C9H9Cl2N3O·HClPurity:≥ 98.0%Color and Shape:White to almost white crystalline powderMolecular weight:282.55N-Carbamimidoyl-2-(2,6-dichlorophenyl)acetamide hydrochloride
CAS:Formula:C9H10Cl3N3OPurity:99%Molecular weight:282.55Guanfacine HCl
CAS:Guanfacine is a centrally acting alpha-2 adrenergic agonist that is used in the treatment of hypertension and attention deficit hyperactivity disorder (ADHD). It is a racemic mixture of two enantiomers, (+) and (-) guanfacine. Guanfacine acts on central alpha-2 receptors to reduce sympathetic outflow from the vasomotor center, which leads to reduced peripheral vascular resistance, decreased blood pressure, and increased heart rate. It also has been shown to increase the release of gamma-aminobutyric acid (GABA), a neurotransmitter that inhibits neuronal activity. Guanfacine is metabolized by CYP3A4 and CYP2D6 enzymes with elimination half-life of 10 hours. The drug has minimal drug interactions due to its low protein binding properties. Guanfacine has been found to be safe for use in humans at doses up to 3 mg/kg/day
Formula:C9H9Cl2N3O·HClPurity:Min. 95%Molecular weight:282.55 g/mol
