Pim-1 kinase inhibitor 10, identified by its CAS number 2918764-57-3, is a chemical compound that serves as an inhibitor of the Pim-1 kinase, an important enzyme involved in various cellular processes, including cell survival and proliferation. This compound is part of a class of small molecules designed to selectively inhibit the activity of Pim kinases, which are implicated in several types of cancer and other diseases. The characteristics of Pim-1 kinase inhibitor 10 include its molecular structure, which typically features specific functional groups that enhance its binding affinity to the target kinase. The compound is often evaluated for its potency, selectivity, and pharmacokinetic properties, which are crucial for its potential therapeutic applications. Additionally, studies may focus on its efficacy in preclinical models, safety profile, and mechanisms of action. Overall, Pim-1 kinase inhibitor 10 represents a promising candidate in the development of targeted cancer therapies, contributing to the ongoing research in kinase inhibition and cancer treatment strategies.

Pim-1 kinase inhibitor 10

2918764-57-3: Pim-1 kinase inhibitor 10, identified by its CAS number 2918764-57-3, is a chemical compound that serves as an inhibitor of the Pim-1 kinase, an important enzyme involved in various cellular processes, including cell survival and proliferation. This compound is part of a class of small molecules designed to selectively inhibit the activity of Pim kinases, which are implicated in several types of cancer and other diseases. The characteristics of Pim-1 kinase inhibitor 10 include its molecular structure, which typically features specific functional groups that enhance its binding affinity to the target kinase. The compound is often evaluated for its potency, selectivity, and pharmacokinetic properties, which are crucial for its potential therapeutic applications. Additionally, studies may focus on its efficacy in preclinical models, safety profile, and mechanisms of action. Overall, Pim-1 kinase inhibitor 10 represents a promising candidate in the development of targeted cancer therapies, contributing to the ongoing research in kinase inhibition and cancer treatment strategies.

<p>Pim-1 Kinase Inhibitor 10 (compound 13a) acts as both a competitive and non-competitive inhibitor of PIM-1/2 kinase, promoting cell apoptosis and displaying anticancer properties. Additionally, this compound triggers the activation of caspase 3/7 [1].</p>

CAS 2918764-57-3

Pim-1 kinase inhibitor 10

Pim-1 kinase inhibitor 10

Ref: TM-T87212