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CAS 2920000-23-1

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  • LZ-007
    Targetmol
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    LZ-007

    CAS:
    LZ-007 is an agonist of the Farnesoid X receptor (FXR), with an EC50 of 51 nM as determined by TR-FRET assay, and an EC50 of 76 nM in HepG2 cells. It exhibits favorable pharmacokinetic properties in SD rats and can improve metabolic dysfunction-associated steatohepatitis induced by high-fat diets and CCl4 in mice.
    Formula:C27H29F3N2O5
    Color and Shape:Solid
    Molecular weight:518.53

    Ref: TM-T203062