CAS 292055-71-1

threo-Dihydro Bupropion Hydrochloride

Controlled Product

CAS: 292055-71-1

Stability Hygroscopic
Applications rac-threo-Dihydro Bupropion Hydrochloride is a metabolite of Bupropion (B689625), a selective inhibitor of dopamine uptake.
References Suckow, R., et al.: Drug Metab Dispos., 14, 692 (1986);

Formula: C₁₃H₂₀ClNO·HCl

Color and Shape: Neat

Molecular weight: 241.763646

Ref: TR-D450473

(S,S)-Dihydro Bupropion Hydrochloride

Controlled Product

CAS: 292055-71-1

Stability Hygroscopic
Applications (S,S)-Dihydro Bupropion is a metabolite of Bupropion (B689625), a selective inhibitor of dopamine uptake.
References Writer, J.H., et. al.: Sci. Total Environ., 461 (2013)

Formula: C₁₃H₂₀ClNO·HCl

Color and Shape: Neat

Molecular weight: 241.76 + (36.46)

Ref: TR-D448290

(S,S)-Dihydro bupropion hydrochloride

Controlled Product

CAS: 292055-71-1

(S,S)-Dihydro bupropion hydrochloride (Bupropion) is an antidepressant that is used for the treatment of major depressive disorder and seasonal affective disorder. It is a racemic mixture of the two enantiomers, (S,S) and (R,R), with the former being more active than the latter. The drug product contains a racemic mixture of (S,S) and (R,R) in a ratio of approximately 97:3. The analytical impurity in this product is N-desmethyl-bupropion. This impurity has not been found to be pharmacologically active. Bupropion may be synthesized by reacting benzaldehyde with propargyl bromide in presence of sodium hydroxide in ethanol to form a cyclic imine intermediate which is then hydrolyzed to yield bupropion

Formula: C₁₃H₂₀ClNO·HCl

Purity: Min. 95%

Molecular weight: 241.76 g/mol

Ref: 3D-SLA05571