CAS 2921-57-5

Methylprednisolone succinate

Description:

Methylprednisolone succinate is a synthetic corticosteroid with anti-inflammatory and immunosuppressive properties, commonly used in the treatment of various conditions such as allergies, autoimmune disorders, and certain types of cancer. It is a derivative of methylprednisolone, which is a modified form of the steroid hormone cortisol. The substance is characterized by its ability to inhibit the release of inflammatory mediators and modulate immune responses. Methylprednisolone succinate is typically administered via injection and is known for its rapid onset of action. Its chemical structure includes a succinate ester, which enhances its solubility and bioavailability. The compound is generally well-tolerated, but potential side effects may include increased risk of infections, gastrointestinal disturbances, and alterations in glucose metabolism. As with other corticosteroids, long-term use requires careful monitoring due to possible adverse effects on various organ systems. Overall, methylprednisolone succinate is a valuable therapeutic agent in managing inflammatory and autoimmune conditions.

Formula: C₂₆H₃₄O₈

InChI: InChI=1S/C26H34O8/c1-14-10-16-17-7-9-26(33,20(29)13-34-22(32)5-4-21(30)31)25(17,3)12-19(28)23(16)24(2)8-6-15(27)11-18(14)24/h6,8,11,14,16-17,19,23,28,33H,4-5,7,9-10,12-13H2,1-3H3,(H,30,31)/t14-,16-,17-,19-,23+,24-,25-,26-/m0/s1

InChI key: InChIKey=IMBXEJJVJRTNOW-XYMSELFBSA-N

SMILES: C[C@@]12[C@]([C@]3([C@@]([C@]4(C)C([C@@H](C)C3)=CC(=O)C=C4)([C@@H](O)C1)[H])[H])(CC[C@@]2(C(COC(CCC(O)=O)=O)=O)O)[H]

Synonyms:

• (6α,11β)-21-(3-Carboxy-1-oxopropoxy)-11,17-dihydroxy-6-methylpregna-1,4-diene-3,20-dione
• 11Beta,17,21-Trihydroxy-6Alpha-Methylpregna-1,4-Diene-3,20-Dione 21-(Hydrogen Succinate)
• 4-{[(6Alpha,11Beta)-11,17-Dihydroxy-6-Methyl-3,20-Dioxopregna-1,4-Dien-21-Yl]Oxy}-4-Oxobutanoic Acid
• 6-Methylprednisolone hemisuccinate
• 6α-Methylprednisolone 21-succinate
• 6α-Methylprednisolone hemisuccinate
• Methylprednisolone 21-hemisuccinate
• Methylprednisolone succinate
• Pregna-1,4-diene-3,20-dione, 11β,17,21-trihydroxy-6α-methyl-, 21-(H succinate)
• Pregna-1,4-diene-3,20-dione, 11β,17,21-trihydroxy-6α-methyl-, 21-(hydrogen succinate)
• Pregna-1,4-diene-3,20-dione, 11β,17,21-trihydroxy-6α-methyl-, 21-succinate

Methylprednisolone Hydrogen Succinate

CAS: 2921-57-5

Color and Shape: Neat

Ref: 61-FOR1515.00

METHYLPREDNISOLONE HYDROGEN SUCCINATE FOR PERFORMANCE TEST CRS

CAS: 2921-57-5

METHYLPREDNISOLONE HYDROGEN SUCCINATE FOR PERFORMANCE TEST CRS

Color and Shape: Powder

Ref: 41-M1755220

METHYLPREDNISOLONE HYDROGEN SUCCINATE CRS

CAS: 2921-57-5

METHYLPREDNISOLONE HYDROGEN SUCCINATE CRS

Formula: C₂₆H₃₄O₈

Color and Shape: Powder

Molecular weight: 474.5434

Ref: 41-M1755200

METHYLPREDNISOLONE HYDROGEN SUCCINATE FOR PEAK IDENTIFICATION CRS

CAS: 2921-57-5

METHYLPREDNISOLONE HYDROGEN SUCCINATE FOR PEAK IDENTIFICATION CRS

Formula: C₂₆H₃₄O₈

Color and Shape: Powder

Molecular weight: 474.5434

Ref: 41-Y0001759

Methylprednisolone Hemisuccinate

CAS: 2921-57-5

Adrenal cortical hormones and their derivatives nesoi

Formula: C₂₆H₃₄O₈

Color and Shape: White Off-White Powder

Molecular weight: 474.22537

Ref: 45-1437009

Methylprednisolone 21-Hemisuccinate (Methylprednisolone Hydrogen Succinate)

CAS: 2921-57-5

Formula: C₂₆H₃₄O₈

Color and Shape: White To Off-White Solid

Molecular weight: 474.55

Ref: 4Z-P-11138

Methylprednisolone succinate

CAS: 2921-57-5

Methylprednisolone succinate

Purity: ≥98%

Molecular weight: 474.54g/mol

Ref: 54-BUP11730

Methylprednisolone Hydrogen Succinate

Controlled Product

CAS: 2921-57-5

Formula: C₂₆H₃₄O₈

Color and Shape: Neat

Molecular weight: 474.54

Ref: 86-MM1515.00

Methylprednisolone succinate

CAS: 2921-57-5

Methylprednisolone succinate (Methylprednisolone hemisuccinate) is a synthetic glucocorticoid and is widely used as an anti-inflammatory agent.

Formula: C₂₆H₃₄O₈

Purity: 98.41% - 99.82%

Color and Shape: White Or Almost-White Solid Powder

Molecular weight: 474.54

Ref: TM-T22367

Methylprednisolone Succinate RS

CAS: 2921-57-5

Color and Shape: White Solid Crystalline Powder

Ref: 2K-1165000021

Methylprednisolone 21-Hemisuccinate

CAS: 2921-57-5

Formula: C₂₆H₃₄O₈

Molecular weight: 474.55

Ref: ST-EA-CP-M14014

6a-Methylprednisolone 21-Hemisuccinate

Controlled Product

CAS: 2921-57-5

Applications 6α-Methylprednisolone 21-Hemisuccinate is a derivative of methylprednisolone (M325934), a glucocorticoid and a anti-inflammatory drug used to treat central nervous system disorders such as multiple sclerosis. 6α-Methylprednisolone 21-Hemisuccinate was examined for potential therapeutic efficacy in a model of neuroinflammation in rats with acute autoimmune encephalomyelitis.
References Gaillard, P.J., et al.: J. Controlled. Release., 164, 364 (2012);

Formula: C₂₆H₃₄O₈

Color and Shape: White To Off-White

Molecular weight: 474.54

Ref: TR-M331195

Methylprednisolone hemisuccinate

Controlled Product

CAS: 2921-57-5

Meghylprednisolone hemisuccinate is a nonsteroidal anti-inflammatory drug (NSAID) that belongs to the group of pharmacological agents. It is used for pain relief in cases of inflammatory bowel disease, and has been shown to be effective against human immunoglobulin A (IgA) nephropathy. Meghylprednisolone hemisuccinate inhibits prostaglandin synthesis by binding to the enzyme cyclooxygenase and blocking the conversion of arachidonic acid to prostaglandins. This drug also blocks the production of leukotrienes, which are mediators of inflammation and tissue injury. Meghylprednisolone hemisuccinate has been shown to be less toxic than methylprednisolone sodium succinate in rats when given at low doses orally, although it has not been studied in humans.

Formula: C₂₆H₃₄O₈

Purity: Min. 95%

Molecular weight: 474.54 g/mol

Ref: 3D-FM39645