CAS 2922-83-0

L-Kynurenine

Description:

L-Kynurenine is an amino acid derivative and a key intermediate in the metabolism of the essential amino acid tryptophan. It is characterized by its role in the kynurenine pathway, which is significant in the biosynthesis of several bioactive compounds, including neurotransmitters and neuroactive metabolites. L-Kynurenine is known for its potential neuroprotective and immunomodulatory properties, making it a subject of interest in research related to neurodegenerative diseases and psychiatric disorders. The compound is typically a yellowish crystalline solid, soluble in water and various organic solvents. Its structure features an indole ring, which is characteristic of tryptophan derivatives, and it can exist in different tautomeric forms. L-Kynurenine has been studied for its effects on the central nervous system, including its influence on serotonin levels and its role in inflammation. Additionally, it has been implicated in various physiological processes, including immune response and oxidative stress regulation. Overall, L-Kynurenine is a significant compound in both biochemical research and potential therapeutic applications.

Formula: C₁₀H₁₂N₂O₃

InChI: InChI=1/C10H12N2O3/c11-7-4-2-1-3-6(7)9(13)5-8(12)10(14)15/h1-4,8H,5,11-12H2,(H,14,15)/t8-/m0/s1

InChI key: InChIKey=YGPSJZOEDVAXAB-QMMMGPOBSA-N

SMILES: C(C[C@@H](C(O)=O)N)(=O)C1=C(N)C=CC=C1

Synonyms:

• (2S)-4-(2-Aminophenyl)-2-azaniumyl-4-oxobutanoate
• (αS)-α,2-Diamino-γ-oxobenzenebutanoic acid
• 3-Anthraniloylalanine
• <span class="text-smallcaps">L</span>-3-(o-Aminobenzoyl)alanine
• <span class="text-smallcaps">L</span>-Kynurenine
• Alanine, 3-anthraniloyl-, <span class="text-smallcaps">L</span>-
• Benzenebutanoic acid, α,2-diamino-γ-oxo-, (S)-
• Benzenebutanoic acid, α,2-diamino-γ-oxo-, (αS)-
• Kynurenin
• Kynurenine
• L-Kynurenine
• Alanine, 3-anthraniloyl-, L-
• β-Anthraniloyl-L-alanine
• L-2-AMINO-3-(2-AMINOBENZOYL)PROPIONIC ACID
• (S)-2-Amino-4-oxo-4-(2-aminophenyl)butanoic acid
• L-Kynurenine Hydrate
• 3-(2-Aminobenzoyl)-L-alanine
• 3-(2-Aminobenzoyl)alanine
• β-Anthraniloyl-L-alanine, L-2-Amino-4-(2-aminophenyl)-4-oxobutanoic acid
• L-kynurenine free base
• (S)-α,2-Diamino-γ-oxobenzenebutanoic acid

L-Kynurenine

CAS: 2922-83-0

Formula: C₁₀H₁₂N₂O₃

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Yellow powder to crystal

Molecular weight: 208.22

Ref: 3B-K0016

L-Kynurenine

CAS: 2922-83-0

Intermediate in the breakdown of tryptophan

Formula: C₁₀H₁₂N₂O₃

Molecular weight: 208.21

Ref: 02-J60199

Benzenebutanoic acid, α,2-diamino-γ-oxo-, (αS)-

CAS: 2922-83-0

Formula: C₁₀H₁₂N₂O₃

Purity: %

Color and Shape: Solid

Molecular weight: 208.2139

Ref: IN-DA002XRH

L-Kynurenine

CAS: 2922-83-0

L-Kynurenine

Purity: ≥98%

Molecular weight: 208.21g/mol

Ref: 54-BUP15764

L-Kynurenine

CAS: 2922-83-0

Formula: C₁₀H₁₂N₂O₃

Purity: (Titration) ≥ 97.0% (dried basis)

Color and Shape: White to yellow or pale brown powder

Molecular weight: 208.21

Ref: 7W-GM4707

(L)-Kynurenine

CAS: 2922-83-0

Formula: C₁₀H₁₂N₂O₃

Color and Shape: Pale Yellow Solid

Molecular weight: 208.22

Ref: 4Z-K-008001

L-Kynurenine-13C4-15N

CAS: 2922-83-0

Formula: C₆₁₃C₄H₁₂N₁₅NO₃

Color and Shape: Pale Yellow Solid

Molecular weight: 213.18

Ref: 4Z-K-008002

L-Kynurenine free base

CAS: 2922-83-0

L-Kynurenine free base

Purity: 98%

Color and Shape: Powder

Molecular weight: 208.21388g/mol

Ref: 54-BIB6088

L-Kynurenine

CAS: 2922-83-0

L-Kynurenine ((S)-Kynurenine)) is an endogenous agonist of aryl hydrocarbon receptor (AHR) ,inhibits allogeneic T cell proliferation. High-Quality, Low-Cost!

Formula: C₁₀H₁₂N₂O₃

Purity: 98.44% - 99.91%

Color and Shape: Light Yellow Crystalline

Molecular weight: 208.21

Ref: TM-T4928

L-Kynurenine-13C6

CAS: 2922-83-0

Formula: C₄₁₃C₆H₁₂N₂O₃

Molecular weight: 214.17

Ref: 4Z-K-008008

L-Kynurenine

CAS: 2922-83-0

Applications L-Kynurenine is a tryptophan metabolite which is a precursor of kynurenic acid (K660500) and an antagonist of N-methyl-aspartate receptor.
References Swartz, K., et al.: J. Neurosci., 10, 2965 (1990);, Hasegawa, H., et al.: Anal. Bioanal. Chem., 377, 886 (2003); Tsai, Y., et al.: Anal. Biochem., 319, 34 (2003); Mitsuhashi, S., et al.: Anal. Chim. Acta, 584, 315 (2007)

Formula: C₁₀H₁₂N₂O₃

Color and Shape: Neat

Molecular weight: 208.21

Ref: TR-K661005

L-Kynurenine-d4 TFA Salt

Controlled Product

CAS: 194546-33-3, 2922-83-0

Applications L-Kynurenine-d4 Trifluoroacetic Acid Salt is the isotope labelled analog of L-Kynurenine. L-Kynurenine is a tryptophan metabolite which is a precursor of kynurenic acid, an antagonist of N-methyl-aspartate receptor.
References Swartz, K., et al.: J. Neurosci., 10, 2965 (1990);, Hasegawa, H., et al.: Anal. Bioanal. Chem., 377, 886 (2003); Tsai, Y., et al.: Anal. Biochem., 319, 34 (2003); Mitsuhashi, S., et al.: Anal. Chim. Acta, 584, 315 (2007)

Formula: C₁₀H₈D₄N₂O₃•x(C₂HF₃O₂)

Color and Shape: Light Yellow To Dark Brown

Molecular weight: 212.2411402

Ref: TR-K661007

L-Kynurenine, free base

CAS: 2922-83-0

Precursor to the excitatory amino acid antagonist kynurenic acid.

Formula: C₁₀H₁₂N₂O₃

Purity: Min. 97.5 Area-%

Molecular weight: 208.22 g/mol

Ref: 3D-K-9020

(S)-2-Amino-4-(2-aminophenyl)-4-oxobutanoic acid

CAS: 2922-83-0

Formula: C₁₀H₁₂N₂O₃

Purity: 95+%

Color and Shape: Liquid, No data available.

Molecular weight: 208.217

Ref: 10-F235607

L-Kynurenine-13C4,15N

Controlled Product

CAS: 2922-83-0

Formula: C₄C₆H₁₂₁₅NNO₃

Color and Shape: Neat

Molecular weight: 213.178

Ref: TR-K661006

Tryptophan EP Impurity C

CAS: 2922-83-0

Formula: C₁₀H₁₂N₂O₃

Molecular weight: 208.22

Ref: ST-EA-CP-T90003