Topo II/HDAC-IN-2, identified by its CAS number 2922269-24-5, is a chemical compound that functions as an inhibitor of both topoisomerase II and histone deacetylases (HDACs). This dual inhibition is significant in cancer research, as it can disrupt cellular processes such as DNA replication and transcription, leading to apoptosis in cancer cells. The compound is characterized by its ability to interfere with the normal function of these enzymes, which play crucial roles in maintaining DNA structure and regulating gene expression. Topo II/HDAC-IN-2 is typically studied in the context of its potential therapeutic applications, particularly in the treatment of various malignancies. Its molecular structure and specific interactions with target enzymes contribute to its efficacy and selectivity, making it a subject of interest in drug development. As with many compounds in this category, understanding its pharmacokinetics, toxicity, and overall biological activity is essential for evaluating its potential as a therapeutic agent.

Topo II/HDAC-IN-2

2922269-24-5: Topo II/HDAC-IN-2, identified by its CAS number 2922269-24-5, is a chemical compound that functions as an inhibitor of both topoisomerase II and histone deacetylases (HDACs). This dual inhibition is significant in cancer research, as it can disrupt cellular processes such as DNA replication and transcription, leading to apoptosis in cancer cells. The compound is characterized by its ability to interfere with the normal function of these enzymes, which play crucial roles in maintaining DNA structure and regulating gene expression. Topo II/HDAC-IN-2 is typically studied in the context of its potential therapeutic applications, particularly in the treatment of various malignancies. Its molecular structure and specific interactions with target enzymes contribute to its efficacy and selectivity, making it a subject of interest in drug development. As with many compounds in this category, understanding its pharmacokinetics, toxicity, and overall biological activity is essential for evaluating its potential as a therapeutic agent.

<p>Topo II/HDAC-IN-2 (8d) demonstrates remarkable dual inhibitory effects on Topo II and HDAC, and also induces apoptosis [1].</p>

CAS 2922269-24-5

Topo II/HDAC-IN-2

Topo II/HDAC-IN-2

Ref: TM-T87549