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CAS 2923313-69-1

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  • PD-L1/HDAC-IN-1
    Targetmol
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    PD-L1/HDAC-IN-1

    CAS:
    <p>PD-L1/HDAC-IN-1 (Compound 14) is an inhibitor of PD-L1 and HDAC, effectively blocking PD-1/PD-L1 interaction as well as HDAC2 and HDAC3 with IC50 values of 88.10, 27.98, and 14.47 nM, respectively. It exhibits mild cytotoxicity in MCF-7 cells (IC50=19.34 μM) and enhances the expression of PD-L1 and CXCL10, promoting antitumor immune responses by recruiting T cell infiltration into the tumor microenvironment (TME).</p>
    Formula:C42H46ClN3O7
    Color and Shape:Solid
    Molecular weight:740.284

    Ref: TM-T205147