GPR183 antagonist-2, identified by its CAS number 2924063-98-7, is a chemical compound that functions as an antagonist of the GPR183 receptor, also known as Epstein-Barr virus-induced gene 3 (EBI3). This receptor is involved in various biological processes, including immune response and cell migration. The characteristics of GPR183 antagonist-2 include its potential role in modulating immune system activities, making it a subject of interest in research related to autoimmune diseases and inflammation. The compound is typically characterized by its specific molecular structure, which allows it to bind selectively to the GPR183 receptor, inhibiting its activity. This inhibition can lead to altered signaling pathways, which may have therapeutic implications. As with many chemical substances, the safety profile, solubility, stability, and pharmacokinetics of GPR183 antagonist-2 are crucial for its application in research and potential clinical settings. Further studies are necessary to fully elucidate its biological effects and therapeutic potential.

GPR183 antagonist-2

2924063-98-7: GPR183 antagonist-2, identified by its CAS number 2924063-98-7, is a chemical compound that functions as an antagonist of the GPR183 receptor, also known as Epstein-Barr virus-induced gene 3 (EBI3). This receptor is involved in various biological processes, including immune response and cell migration. The characteristics of GPR183 antagonist-2 include its potential role in modulating immune system activities, making it a subject of interest in research related to autoimmune diseases and inflammation. The compound is typically characterized by its specific molecular structure, which allows it to bind selectively to the GPR183 receptor, inhibiting its activity. This inhibition can lead to altered signaling pathways, which may have therapeutic implications. As with many chemical substances, the safety profile, solubility, stability, and pharmacokinetics of GPR183 antagonist-2 are crucial for its application in research and potential clinical settings. Further studies are necessary to fully elucidate its biological effects and therapeutic potential.

<p>GPR183 antagonist-2 (compound 32), a selective antagonist of GPR183, exhibits excellent water solubility and pharmacokinetic properties. This compound effectively diminishes paw and joint swelling, and reduces gene expression of pro-inflammatory cytokines (MCP-1, MMPs, and VEGF) in a dose-dependent manner within a collagen-induced arthritis (CIA) mouse model. GPR183 antagonist-2 is applicable in researching autoimmune diseases [1].</p>

CAS 2924063-98-7

GPR183 antagonist-2

GPR183 antagonist-2

Ref: TM-T86519