GPR183-IN-2, identified by its CAS number 2924064-10-6, is a chemical compound that serves as an inhibitor of the G protein-coupled receptor GPR183, also known as Epstein-Barr virus-induced gene 2 (EBI2). This receptor plays a significant role in immune responses and the regulation of lymphocyte migration. The compound is characterized by its specific binding affinity to GPR183, which can influence various biological pathways, particularly in the context of immune cell trafficking and inflammation. GPR183-IN-2 is typically studied in the context of immunology and pharmacology, where it may have potential therapeutic applications in autoimmune diseases and other conditions involving dysregulated immune responses. Its chemical structure and properties, while not specified here, would include functional groups that facilitate its interaction with the receptor. As research progresses, the understanding of its efficacy, safety, and potential side effects will be crucial for its development as a therapeutic agent.

GPR183-IN-2

2924064-10-6: GPR183-IN-2, identified by its CAS number 2924064-10-6, is a chemical compound that serves as an inhibitor of the G protein-coupled receptor GPR183, also known as Epstein-Barr virus-induced gene 2 (EBI2). This receptor plays a significant role in immune responses and the regulation of lymphocyte migration. The compound is characterized by its specific binding affinity to GPR183, which can influence various biological pathways, particularly in the context of immune cell trafficking and inflammation. GPR183-IN-2 is typically studied in the context of immunology and pharmacology, where it may have potential therapeutic applications in autoimmune diseases and other conditions involving dysregulated immune responses. Its chemical structure and properties, while not specified here, would include functional groups that facilitate its interaction with the receptor. As research progresses, the understanding of its efficacy, safety, and potential side effects will be crucial for its development as a therapeutic agent.

<p>GPR183-IN-2 (compound 23) is an effective, orally active inhibitor of GPR183, displaying an IC50 value of 39.45 nM in Ca2+ mobilization assays. This compound has potential applications in research related to cancer, autoimmune diseases, pain, and osteoporosis.</p>

CAS 2924064-10-6

GPR183-IN-2

GPR183-IN-2

Ref: TM-T88500