Ack1 inhibitor 1, identified by its CAS number 2924415-92-7, is a small molecule that functions as an inhibitor of the Ack1 (Activated Cdc42-associated kinase 1) enzyme, which is involved in various cellular processes, including cell signaling, proliferation, and survival. This compound is characterized by its ability to selectively inhibit Ack1 activity, thereby impacting pathways associated with cancer progression and metastasis. Its chemical structure typically includes specific functional groups that contribute to its binding affinity and selectivity for the Ack1 target. The inhibition of Ack1 has potential therapeutic implications, particularly in oncology, as it may help in the development of treatments for cancers where Ack1 is overexpressed or hyperactivated. Additionally, Ack1 inhibitor 1 may be utilized in research settings to elucidate the role of Ack1 in cellular mechanisms and to explore its potential as a drug candidate. As with many small molecule inhibitors, its efficacy and safety profile would be evaluated through preclinical and clinical studies.

Ack1 inhibitor 1

2924415-92-7: Ack1 inhibitor 1, identified by its CAS number 2924415-92-7, is a small molecule that functions as an inhibitor of the Ack1 (Activated Cdc42-associated kinase 1) enzyme, which is involved in various cellular processes, including cell signaling, proliferation, and survival. This compound is characterized by its ability to selectively inhibit Ack1 activity, thereby impacting pathways associated with cancer progression and metastasis. Its chemical structure typically includes specific functional groups that contribute to its binding affinity and selectivity for the Ack1 target. The inhibition of Ack1 has potential therapeutic implications, particularly in oncology, as it may help in the development of treatments for cancers where Ack1 is overexpressed or hyperactivated. Additionally, Ack1 inhibitor 1 may be utilized in research settings to elucidate the role of Ack1 in cellular mechanisms and to explore its potential as a drug candidate. As with many small molecule inhibitors, its efficacy and safety profile would be evaluated through preclinical and clinical studies.

<p>Ack1 inhibitor 1 is a potent and selective orally active inhibitor of ACK1 kinase, with an IC50 value of 2.1 nM. It effectively inhibits the phosphorylation of ACK1 and the activation of downstream AKT, demonstrating anti-tumor activity [1].</p>

CAS 2924415-92-7

Ack1 inhibitor 1

Ack1 inhibitor 1

Ref: TM-T85583