CAS 2925590-71-0

tri-GalNAc-PEG3-Azide

CAS: 2925590-71-0

Tri-GalNAc-PEG3-Azide is a specialized compound designed for lysosomal targeting chimera (LYTAC) research, featuring three asialoglycoprotein receptor (ASGPR)

Formula: C₇₀H₁₂₅N₁₃O₃₁

Color and Shape: Solid

Molecular weight: 1644.83

Ref: TM-T83964

Tri-b-GalNAc-PEG3-azide

CAS: 2925590-71-0

Tri-GalNAc-PEG3-azide is an ASGPR-targeted ligand. This molecule contains three beta-GalNAc sugar units (trivalent) linked by a discrete and uniform PEG3 spacer. The spacer terminates with a reactive azide group for conjugation to other molecules. Upon binding to ASGPR, tri-GalNAc-PEG3-azide conjugates are efficiently taken up by cells (endocytosis) due to the trivalent GalNAc recognition. This property allows researchers to deliver various cargo, like RNA or Cas9 complexes, specifically to liver cells (hepatocytes) and permits using tri-GalNAc-PEG3-Azide to create targeted drug delivery systems (LYTACs) or labeled with dyes for imaging tissues.

Formula: C₇₀H₁₂₅N₁₃O₃₁

Purity: Min. 95%

Molecular weight: 1,644.8 g/mol

Ref: 3D-MT184238