CAS 2928537-98-6

1-Piperazinecarbodithioic acid, 4-[5-[(3,4-dihydro-4-oxo-1-phthalazinyl)methyl]-2-fluorobenzoyl]-, 7-(hydroxyamino)-7-oxoheptyl ester

Description:

1-Piperazinecarbodithioic acid, 4-[5-[(3,4-dihydro-4-oxo-1-phthalazinyl)methyl]-2-fluorobenzoyl]-, 7-(hydroxyamino)-7-oxoheptyl ester is a complex organic compound characterized by its unique structural features, including a piperazine ring, a carbodithioic acid moiety, and a phthalazinyl group. The presence of a fluorobenzoyl substituent and a hydroxyamino group contributes to its potential reactivity and biological activity. This compound may exhibit properties such as solubility in organic solvents, moderate stability under standard conditions, and potential interactions with biological targets due to its functional groups. Its intricate structure suggests possible applications in medicinal chemistry, particularly in the development of pharmaceuticals or agrochemicals. The CAS number 2928537-98-6 serves as a unique identifier for this substance, facilitating its recognition in chemical databases and literature. Further studies would be necessary to elucidate its specific properties, mechanisms of action, and potential uses in various fields.

Formula: C₂₈H₃₂FN₅O₄S₂

Synonyms:

• 1-Piperazinecarbodithioic acid, 4-[5-[(3,4-dihydro-4-oxo-1-phthalazinyl)methyl]-2-fluorobenzoyl]-, 7-(hydroxyamino)-7-oxoheptyl ester

DLC-50

CAS: 2928537-98-6

DLC-50 is a dual inhibitor of PARP-1 and HDAC-1, exhibiting IC50 values of 1.2 nM and 31 nM respectively. It hinders the proliferation of cancer cells such as MDA-MB-436, MDA-MB-231, and MCF-7 with IC50 values of 0.3 μM, 2.7 μM, and 2.41 μM respectively. Additionally, DLC-50 induces apoptosis in MDA-MB-231 cells and causes cell cycle arrest at the G2 phase.

Formula: C₂₈H₃₂FN₅O₄S₂

Color and Shape: Solid

Molecular weight: 585.71

Ref: TM-T88516