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CAS 29331-92-8

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Licarbazepine

Description:
Licarbazepine is an anticonvulsant medication primarily used in the treatment of epilepsy and neuropathic pain. It is a derivative of carbamazepine and functions as a sodium channel blocker, stabilizing neuronal membranes and reducing the frequency of seizures. The chemical formula of Licarbazepine reflects its complex structure, which includes a bicyclic system. It is known for its favorable pharmacokinetic profile, including good oral bioavailability and a relatively long half-life, allowing for less frequent dosing. Licarbazepine is also characterized by its ability to undergo metabolic conversion to its active form, which contributes to its therapeutic effects. Common side effects may include dizziness, drowsiness, and gastrointestinal disturbances, although it is generally well-tolerated. As with other antiepileptic drugs, monitoring for potential interactions with other medications is essential. Overall, Licarbazepine represents a valuable option in the management of seizure disorders and certain types of pain, with ongoing research into its broader therapeutic applications.
Formula:C15H14N2O2
InChI:InChI=1/C15H14N2O2/c16-15(19)17-12-7-3-1-5-10(12)9-14(18)11-6-2-4-8-13(11)17/h1-8,14,18H,9H2,(H2,16,19)
InChI key:InChIKey=BMPDWHIDQYTSHX-UHFFFAOYSA-N
SMILES:C(N)(=O)N1C=2C(C(O)CC=3C1=CC=CC3)=CC=CC2
Synonyms:
  • 10,11-Dihydro-10-hydroxy-5H-dibenz[b,f]azepine-5-carboxamide
  • 10,11-Dihydro-10-hydroxy-5H-dibenzo[b,f]azepine-5-carboxamide
  • 10,11-Dihydro-10-hydroxycarbamazepine
  • 10-Hydroxy-10,11-dihydrocarbamazepine
  • 10-Hydroxy-10,11-dihydrocarbamezepine
  • 10-hydroxy-10,11-dihydro-5H-dibenzo[b,f]azepine-5-carboxamide
  • 5H-Dibenz[b,f]azepine-5-carboxamide, 10,11-dihydro-10-hydroxy-
  • Bia 2-005
  • Gp-47779
  • Licarbazepine
  • See more synonyms
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