CAS 29334-16-5

4-Bromo-α-phenylbenzenemethanol

Description:

4-Bromo-α-phenylbenzenemethanol, also known by its CAS number 29334-16-5, is an organic compound characterized by the presence of a bromine atom and a phenyl group attached to a benzyl alcohol structure. This compound typically appears as a solid or crystalline substance and is soluble in organic solvents, reflecting its hydrophobic characteristics due to the aromatic rings. The bromine substituent introduces both steric and electronic effects, which can influence its reactivity and interactions in chemical reactions. The hydroxyl (-OH) group in the benzyl alcohol moiety contributes to its potential as a hydrogen bond donor, making it relevant in various chemical applications, including synthesis and as a potential intermediate in organic reactions. Additionally, the presence of the bromine atom may enhance its reactivity in nucleophilic substitution reactions. Overall, 4-Bromo-α-phenylbenzenemethanol is of interest in both academic research and industrial applications due to its unique structural features and reactivity profile.

Formula: C₁₃H₁₁BrO

InChI: InChI=1S/C13H11BrO/c14-12-8-6-11(7-9-12)13(15)10-4-2-1-3-5-10/h1-9,13,15H

InChI key: InChIKey=WTIWDBNPPSHSCB-UHFFFAOYSA-N

SMILES: C(O)(C1=CC=C(Br)C=C1)C2=CC=CC=C2

Synonyms:

• (4-Bromophenyl)(Phenyl)Methanol
• (4-Bromophenyl)phenylmethanol
• (R)-(4-bromophenyl)(phenyl)methanol
• (p-Bromophenyl)-α-phenylmethanol
• 4-(1-Hydroxybenzyl)bromobenzene
• 4-Bromo-α-phenylbenzenemethanol
• 4-Bromobenzhydrol
• Benzenemethanol, 4-bromo-α-phenyl-
• Benzhydrol, 4-bromo-
• Benzohydrol, 4-bromo-
• NSC 89817
• p-Bromobenzhydrol
• α-(4-Bromophenyl)benzenemethanol
• α-Phenyl-p-bromobenzyl alcohol

4-Bromobenzhydrol

CAS: 29334-16-5

Formula: C₁₃H₁₁BrO

Purity: >97.0%(GC)

Color and Shape: White to Light yellow to Light orange powder to crystal

Molecular weight: 263.13

Ref: 3B-B4680

Benzenemethanol, 4-bromo-α-phenyl-

CAS: 29334-16-5

Formula: C₁₃H₁₁BrO

Purity: 95%

Color and Shape: Solid

Molecular weight: 263.1298

Ref: IN-DA002Y35

4-Bromo-α-phenylbenzenemethanol (4-Bromobenzhydrol)

CAS: 29334-16-5

Color and Shape: Neat

Ref: 86-MM0640.02

4-Bromobenzhydrol

CAS: 29334-16-5

4-Bromobenzhydrol

Purity: 96%

Molecular weight: 263.13g/mol

Ref: 54-OR4692

4-Bromobenzhydrol

CAS: 29334-16-5

4-Bromobenzhydrol is a potent inhibitor of the enzyme histamine N-methyltransferase that is used in the treatment of chronic inflammatory disorders. In pharmacological tests, 4-bromobenzhydrol has been shown to be an inhibitor of acidic aldehyde reactions and also inhibits hypophosphorous acid formation. This drug also reacts with serum albumin, ethanolamine, and ethylene oxide to form a model protein. 4-Bromobenzhydrol has been shown to have immunosuppressive activity by inhibiting the T cell response.

Formula: C₁₃H₁₁BrO

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 263.13 g/mol

Ref: 3D-FB70740

p-Bromobenzhydrol

CAS: 29334-16-5

Formula: C₁₃H₁₁BrO

Purity: 98%

Color and Shape: Solid

Molecular weight: 263.134

Ref: 10-F018245

4-Bromo-α-phenylbenzenemethanol

Controlled Product

CAS: 29334-16-5

Applications 4-Bromo-α-phenylbenzenemethanol is used in the synthesis of diarylmethylpiperazines as potent and selective nonpeptidic δ-opioid receptor agonists. Is used in the ysnthesis of bronsted acid-catalyzed benzylation of 1,3-dicarbonyl derivatives.
References Plobeck, N. et al.: J. Med. Chem., 43, 3878 (2000); Sanz, R. et al.: Org. Lett., 9, 2027 (2007);

Formula: C₁₃H₁₁BrO

Color and Shape: Neat

Molecular weight: 263.13

Ref: TR-B680270