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CAS 2934561-88-1

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Thalidomide-O-PEG4-amine TFA

Description:
Thalidomide-O-PEG4-amine TFA is a synthetic compound that combines the thalidomide structure with a polyethylene glycol (PEG) moiety and an amine functional group, typically used in pharmaceutical applications. The PEG segment enhances the solubility and bioavailability of the compound, while the amine group can facilitate further chemical modifications or conjugations. Thalidomide itself is known for its immunomodulatory and anti-inflammatory properties, originally developed as a sedative and later withdrawn due to teratogenic effects. The TFA (trifluoroacetic acid) component often indicates that the compound is in its salt form, which can influence its stability and solubility. This compound may be of interest in drug development, particularly in targeted therapies or as a part of conjugates for delivering therapeutic agents. Its characteristics, including molecular weight, solubility, and reactivity, would depend on the specific structural features imparted by the thalidomide and PEG components. As with any chemical substance, safety and handling precautions should be observed, especially given the historical context of thalidomide.
Synonyms:
  • Thalidomide-O-PEG4-amine TFA
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