CAS 293735-04-3

des-​Gln14-​Ghrelin

CAS: 293735-04-3

Endogenous rat ghrelin gene variant binds GHS-R1a; strong Ca2+ release (EC50=2.4 nM); boosts GH secretion in vivo.

Formula: C₁₄₂H₂₃₇N₄₃O₄₀

Purity: 98%

Color and Shape: Solid

Molecular weight: 3186.7

Ref: TM-TP2032

des-Gln14-Ghrelin (rat)

CAS: 293735-04-3

Ghrelin is a peptide hormone that is produced by the stomach and plays an important role in regulating appetite. Ghrelin stimulates hunger by activating the ghrelin receptor, which is found on cells throughout the body. The ghrelin receptor has been shown to be a G-protein coupled receptor (GPCR), which has seven transmembrane domains with intracellular loops that form a ligand binding pocket. Ghrelin binds to its receptor, leading to activation of the G protein and subsequent opening of ion channels. This leads to depolarization of the cell membrane, which creates an action potential that ultimately triggers neurotransmitter release from the neuron. Des-Gln14-Ghrelin (rat) is a synthetic analog of ghrelin that may be used as a research tool for studying ion channels or protein interactions.

Formula: C₁₄₂H₂₃₇N₄₃O₄₀

Purity: Min. 95%

Molecular weight: 3,186.7 g/mol

Ref: 3D-TLA73504