CAS 293754-55-9

N-(2,2,2-Trifluoroethyl)-N-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]benzenesulfonamide

Description:

N-(2,2,2-Trifluoroethyl)-N-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]benzenesulfonamide, with CAS number 293754-55-9, is a synthetic organic compound characterized by its complex structure featuring multiple trifluoromethyl groups. This compound belongs to the class of sulfonamides, which are known for their diverse applications in pharmaceuticals and agrochemicals. The presence of trifluoroethyl and trifluoromethyl groups imparts unique properties, such as increased lipophilicity and potential bioactivity, making it of interest in medicinal chemistry. The sulfonamide functional group contributes to its ability to interact with biological targets, potentially influencing enzyme activity or receptor binding. Additionally, the compound's stability and solubility characteristics are influenced by its fluorinated groups, which can enhance its resistance to metabolic degradation. Overall, this compound exemplifies the design of fluorinated molecules for specific therapeutic applications, highlighting the importance of fluorine in modifying the physical and chemical properties of organic compounds.

Formula: C₁₇H₁₂F₉NO₃S

InChI: InChI=1/C17H12F9NO3S/c18-14(19,20)10-27(31(29,30)13-4-2-1-3-5-13)12-8-6-11(7-9-12)15(28,16(21,22)23)17(24,25)26/h1-9,28H,10H2

InChI key: InChIKey=SGIWFELWJPNFDH-UHFFFAOYSA-N

SMILES: c1ccc(cc1)S(=O)(=O)N(CC(F)(F)F)c1ccc(cc1)C(C(F)(F)F)(C(F)(F)F)O

Synonyms:

• Benzenesulfonamide, N-(2,2,2-trifluoroethyl)-N-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]-
• N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]-N-(2,2,2-trifluoroethyl)benzenesulfonamide
• T 1317
• T-0901317
• To 091317
• To 901317
• To 90317
• N-(2,2,2-TRIFLUOROETHYL)-N-[4-[2,2,2-TRIFLUORO-1-HYDROXY-1-(TRIFLUOROMETHYL)ETHYL]PHENYL]BENZENESULFONAMIDE
• T0901317
• T0901317;T 0901317; T-0901317
• CS-721
• N-(2,2,2-Trifluoroethyl)-N-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]

N-(4-(1,1,1,3,3,3-Hexafluoro-2-Hydroxypropan-2-yl)Phenyl)-N-(2,2,2-Trifluoroethyl)Benzenesulfonamide

CAS: 293754-55-9

N-(4-(1,1,1,3,3,3-Hexafluoro-2-Hydroxypropan-2-yl)Phenyl)-N-(2,2,2-Trifluoroethyl)Benzenesulfonamide

Purity: 95%

Molecular weight: 481.33g/mol

Ref: 54-PC108638

T0901317

Controlled Product

CAS: 293754-55-9

Applications T0901317 is a potent and selective agonist for both liver x receptor (LXR) and farnesoid X receptor (FXR). References Houck, K., et al.: Mol. Genet. Metab., 83, 184 (2004); Goodwin, B., et al.: Mol. Endocr., 17, 386 (2003)

Formula: C₁₇H₁₂F₉NO₃S

Color and Shape: Neat

Molecular weight: 481.33

Ref: TR-T002000

T0901317

CAS: 293754-55-9

T0901317

Purity: ≥98%

Molecular weight: 481.33g/mol

Ref: 54-BUP15543

T0901317

CAS: 293754-55-9

Formula: C₁₇H₁₂NSO₃F₉

Molecular weight: 481.33

Ref: 7W-GL6126

T 0901317

CAS: 293754-55-9

Formula: C₁₇H₁₂F₉NO₃S

Purity: >98.0%(HPLC)(qNMR)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 481.33

Ref: 3B-T4241

T 0901317

CAS: 293754-55-9

Agonist of liver X receptors

Formula: C₁₇H₁₂F₉NO₃S

Purity: Min. 95%

Molecular weight: 481.33 g/mol

Ref: 3D-FT103794

T0901317

CAS: 293754-55-9

T0901317 is a potent and selective agonist for both LXR and FXR, with EC50 of ~50 nM and 5 μM, respectively; it inhibits nuclear factor/κB (NF/κB).

Formula: C₁₇H₁₂F₉NO₃S

Purity: 98% - 99.64%

Color and Shape: Solid

Molecular weight: 481.33

Ref: TM-T6690

Benzenesulfonamide, N-(2,2,2-trifluoroethyl)-N-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]-

CAS: 293754-55-9

Formula: C₁₇H₁₂F₉NO₃S

Purity: 95%

Color and Shape: Solid

Molecular weight: 481.3327

Ref: IN-DA002Y7U