Avibactam sodium hydrate, also known as NXL 104 hydrate, is a synthetic β-lactamase inhibitor that is primarily used in combination with certain antibiotics to enhance their efficacy against resistant bacterial strains. It is characterized by its ability to inhibit a broad range of β-lactamases, including class A and some class C enzymes, which are responsible for antibiotic resistance. This compound is typically presented as a white to off-white solid and is soluble in water, which facilitates its use in pharmaceutical formulations. Avibactam sodium hydrate has a molecular formula that reflects its sodium salt form, and its structure includes a bicyclic core that is crucial for its mechanism of action. The compound is administered parenterally and is primarily investigated for its potential in treating infections caused by multidrug-resistant Gram-negative bacteria. Its development represents a significant advancement in the fight against antibiotic resistance, making it a valuable asset in modern antimicrobial therapy.

Avibactam sodium hydrate (NXL 104 hydrate)

2938989-90-1: Avibactam sodium hydrate, also known as NXL 104 hydrate, is a synthetic β-lactamase inhibitor that is primarily used in combination with certain antibiotics to enhance their efficacy against resistant bacterial strains. It is characterized by its ability to inhibit a broad range of β-lactamases, including class A and some class C enzymes, which are responsible for antibiotic resistance. This compound is typically presented as a white to off-white solid and is soluble in water, which facilitates its use in pharmaceutical formulations. Avibactam sodium hydrate has a molecular formula that reflects its sodium salt form, and its structure includes a bicyclic core that is crucial for its mechanism of action. The compound is administered parenterally and is primarily investigated for its potential in treating infections caused by multidrug-resistant Gram-negative bacteria. Its development represents a significant advancement in the fight against antibiotic resistance, making it a valuable asset in modern antimicrobial therapy.

Avibactam sodium hydrate (NXL-104 hydrate) is a β-lactamase inhibitor, inhibiting β-lactamases TEM-1 and CTX-M-15.

CAS 2938989-90-1

Avibactam sodium hydrate (NXL 104 hydrate)

Avibactam sodium hydrate

Ref: TM-T60711