CAS 294-93-9: 12-Crown-4

Description: 12-Crown-4 is a cyclic polyether belonging to the crown ether family, characterized by its ability to selectively bind cations, particularly alkali metals like sodium and potassium. Its molecular structure consists of a 12-membered ring containing four ether oxygen atoms, which create a cavity that can encapsulate cations due to the size and geometry of the ring. This selective binding is attributed to the electron-donating nature of the oxygen atoms, which stabilize the cation through coordination. 12-Crown-4 is typically a colorless, crystalline solid at room temperature and is soluble in polar organic solvents such as methanol and acetonitrile. It is widely used in various applications, including extraction processes, ion-selective electrodes, and as a phase transfer catalyst in organic synthesis. The compound's ability to form complexes with metal ions makes it valuable in analytical chemistry and materials science. Additionally, its unique properties have led to research in areas such as supramolecular chemistry and drug delivery systems.

Formula: C₈H₁₆O₄

InChI: InChI=1S/C8H16O4/c1-2-10-5-6-12-8-7-11-4-3-9-1/h1-8H2

InChI key: InChIKey=XQQZRZQVBFHBHL-UHFFFAOYSA-N

SMILES: O1CCOCCOCCOCC1

Synonyms:

• 1,4,7,10-Tetraoxaciclododecano
• 1,4,7,10-Tetraoxacyclododecan
• 1,4,7,10-Tetraoxacyclododecane
• 1,4,7,10-Tetraoxycyclododecane
• 12-Crown 4-Ether
• Crown
• Crown Ether/12-Crown-4
• Eoct
• Ethylene oxide cyclic tetramer
• Lithium ionophore V
• 12C4
• 12-Crown-4

12-Crown-4, 98%

CAS: 294-93-9

It serves as an aprotic solvent for alkali metals, the sodium solution is a strong …

• Formula: C₈H₁₆O₄
• Purity: 98%
• Color and Shape: Clear colorless to pale yellow, Liquid
• Molecular weight: 176.21

12-Crown-4

CAS: 294-93-9

• Formula: C₈H₁₆O₄
• Purity: 98%
• Color and Shape: Liquid
• Molecular weight: 176.2102

12-Crown-4

CAS: 294-93-9

12-Crown-4 dissolves Aβ40 fibrils by penetrating their hydrophobic core to interact with crucial residues.

• Formula: C₈H₁₆O₄
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 176.21

12-Crown-4-ether

CAS: 294-93-9

• Color and Shape: Colourless Liquid
• Molecular weight: 176.21g/mol

12-Crown-4

CAS: 294-93-9

• Formula: C₈H₁₆O₄
• Molecular weight: 176.22

12-Crown-4, 97%

CAS: 294-93-9

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. …

• Formula: C₈H₁₆O₄
• Purity: 97%
• Color and Shape: Liquid after melting, Clear colorless to light yellow
• Molecular weight: 176.21

12-Crown 4-Ether

CAS: 294-93-9

• Formula: C₈H₁₆O₄
• Purity: >95.0%(GC)
• Color and Shape: Colorless to Almost colorless clear liquid
• Molecular weight: 176.21

12-Crown-4

CAS: 294-93-9

Applications 12-CROWN-4 (cas# 294-93-9) is a useful research chemical. Not a dangerous good if item …

• Formula: C₈H₁₆O₄
• Color and Shape: Neat
• Molecular weight: 176.21

12-Crown-4

CAS: 294-93-9

12-Crown-4 is a crown ether that has been shown to bind lithium ions. 12-Crown-4 has …

• Formula: C₈H₁₆O₄
• Purity: Min. 95%
• Molecular weight: 176.21 g/mol