IR-117-17, identified by its CAS number 2940241-38-1, is a chemical substance that falls under the category of organophosphorus compounds. While specific details about its characteristics may not be widely available, organophosphorus compounds are generally known for their diverse applications, including use in agriculture as pesticides and in various industrial processes. These compounds often exhibit properties such as high reactivity due to the presence of phosphorus, which can form stable bonds with oxygen and sulfur. Additionally, they may possess varying degrees of toxicity, particularly in relation to their effects on the nervous system, as many organophosphates are known inhibitors of acetylcholinesterase. The physical state, solubility, and stability of IR-117-17 would depend on its molecular structure and functional groups. For precise information regarding its safety, handling, and specific applications, consulting safety data sheets or scientific literature is recommended.

IR-117-17 is an ionizable cationic and biodegradable amino lipid.1 It has been used in the generation of lipid nanoparticles (LNPs). Nebulized administration of LNPs containing IR-117-17 and the cationic lipid 1,2-dioleoyl-2-trimethylammoniumpropane (1,2-DOTAP; Item No. 15110), among other components, and encapsulating reporter mRNA induce luciferase luminescence in the lung and nasal passages in mice. Nebulized administration of the same LNP formulation but encapsulating Cre mRNA induces the expression of Cre in cells of the large and small airways, as well as alveolar macrophages and epithelial cells, in Ai14 mice engineered to express the fluorescent protein tdTomato upon translation of Cre.WARNING This product is not for human or veterinary use.

IR-117-17

2940241-38-1: IR-117-17, identified by its CAS number 2940241-38-1, is a chemical substance that falls under the category of organophosphorus compounds. While specific details about its characteristics may not be widely available, organophosphorus compounds are generally known for their diverse applications, including use in agriculture as pesticides and in various industrial processes. These compounds often exhibit properties such as high reactivity due to the presence of phosphorus, which can form stable bonds with oxygen and sulfur. Additionally, they may possess varying degrees of toxicity, particularly in relation to their effects on the nervous system, as many organophosphates are known inhibitors of acetylcholinesterase. The physical state, solubility, and stability of IR-117-17 would depend on its molecular structure and functional groups. For precise information regarding its safety, handling, and specific applications, consulting safety data sheets or scientific literature is recommended.

<p>IR-117-17 is an ionizable cationic amino lipid that targets the airways. It is degradable via esterase cleavage, making it less likely to accumulate with repeated dosing.</p>

CAS 2940241-38-1

IR-117-17

IR-117-17

Ref: TM-T201180