CAS 2942-59-8

2-Chloronicotinic acid

Description:

2-Chloronicotinic acid is an aromatic compound that belongs to the class of chlorinated pyridine carboxylic acids. It features a pyridine ring substituted with a carboxylic acid group and a chlorine atom at the second position. This compound is typically a white to off-white crystalline solid, exhibiting moderate solubility in water and higher solubility in organic solvents. Its molecular formula is C6H4ClNO2, and it has a molecular weight that reflects the presence of the chlorine atom and the carboxylic acid functional group. 2-Chloronicotinic acid is known for its applications in organic synthesis, particularly as an intermediate in the production of pharmaceuticals and agrochemicals. It can participate in various chemical reactions, including nucleophilic substitutions and coupling reactions, making it a valuable building block in synthetic chemistry. Additionally, its structural features may impart biological activity, which has led to research into its potential therapeutic uses. Safety data indicates that, like many chlorinated compounds, it should be handled with care due to potential toxicity and environmental concerns.

Formula: C₆H₄ClNO₂

InChI: InChI=1S/C6H4ClNO2/c7-5-4(6(9)10)2-1-3-8-5/h1-3H,(H,9,10)

InChI key: InChIKey=IBRSSZOHCGUTHI-UHFFFAOYSA-N

SMILES: C(O)(=O)C1=C(Cl)N=CC=C1

Synonyms:

• 2-Chloro-3-pyridinecarboxylic acid
• 3-Carboxy-2-chloropyridine
• 3-Pyridinecarboxylic acid, 2-chloro-
• Akos Bbs-00004231
• NSC 378
• Nicotinic acid, 2-chloro-
• Rarechem Al Bo 0287
• CNIS
• 2-Chloronicotinic acid

2-Chloronicotinic Acid

CAS: 2942-59-8

Formula: C₆H₄ClNO₂

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Light yellow to Light orange powder to crystal

Molecular weight: 157.55

Ref: 3B-C1108

2-Chloronicotinic acid, 99%

CAS: 2942-59-8

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₆H₄ClNO₂

Purity: 99%

Color and Shape: White to cream, Powder

Molecular weight: 157.55

Ref: 02-A17082

NIFLUMIC ACID IMPURITY A CRS

CAS: 2942-59-8

NIFLUMIC ACID IMPURITY A CRS

Ref: 41-Y0000825

Flunixin Related Compound A (2-Chloronicotinic acid)

CAS: 2942-59-8

Compounds containing an unfused pyridine ring in the structure, nesoi

Formula: C₆H₄ClNO₂

Color and Shape: Cream Powder

Molecular weight: 156.99306

Ref: 45-1274629

3-Pyridinecarboxylic acid, 2-chloro-

CAS: 2942-59-8

Formula: C₆H₄ClNO₂

Purity: 95%

Color and Shape: Solid

Molecular weight: 157.5545

Ref: IN-DA002YCO

2-Chloronicotinic acid

CAS: 2942-59-8

Formula: C₆H₄ClNO₂

Purity: ≥ 98.0%

Color and Shape: White to off-white powder or crystalline powder

Molecular weight: 157.56

Ref: 7W-GK0167

2-Chloronicotinic acid

CAS: 2942-59-8

2-Chloronicotinic acid

Formula: C₆H₄ClNO₂

Purity: 98%

Color and Shape: white to off-white crystalline powder

Molecular weight: 157.55446g/mol

Ref: 54-OR5074

2-Chloronicotinic acid

CAS: 2942-59-8

Formula: C₆H₄ClNO₂

Color and Shape: Neat

Molecular weight: 157.55

Ref: 04-C11451900

Flunixin Meglumine EP Impurity A (Niflumic Acid EP Impurity A)

Controlled Product

CAS: 2942-59-8

Formula: C₆H₄ClNO₂

Color and Shape: Neat

Molecular weight: 157.55

Ref: 86-MM0915.01

Flunixin Meglumine EP Impurity A (Niflumic Acid EP Impurity A)

CAS: 2942-59-8

Formula: C₆H₄ClNO₂

Molecular weight: 157.55

Ref: 4Z-F-663

Flunixin EP Impurity A

CAS: 2942-59-8

Formula: C₆H₄ClNO₂

Molecular weight: 157.55

Ref: ST-EA-CP-F61008

Niflumic Acid EP Impurity A

CAS: 2942-59-8

Formula: C₆H₄ClNO₂

Molecular weight: 157.55

Ref: ST-EA-CP-N78001

2-Chloronicotinic Acid

Controlled Product

CAS: 2942-59-8

Applications 2-Chloronicotinic Acid is used in the preparation of 4-thiazolidinone derivatives and Schiff bases displaying antimicrobial activity.
References Patel, N. et al.: Saudi Pharm. J., 18, 129 (2010); Patel, N. et al.: J. Sci. Islam Repub. Iran., 21, 121 (2010);

Formula: C₆H₄ClNO₂

Color and Shape: Neat

Molecular weight: 157.55

Ref: TR-C370920

2-Chloronicotinic acid

CAS: 2942-59-8

2-Chloronicotinic acid is a chemical compound that belongs to the group of phosphorus compounds. It is a colorless liquid that is soluble in water and has a pungent odor. 2-Chloronicotinic acid can be found in wastewater treatment, as it binds strongly to phosphorus compounds. It also participates in the Suzuki coupling reaction with various organometallic catalysts, such as palladium and nickel, to produce amides and n-oxides. 2-Chloronicotinic acid inhibits the growth of Pseudomonas aeruginosa and other bacteria by binding to the bacterial ribosome and inhibiting protein synthesis. 2-Chloronicotinic acid has been shown to inhibit prostaglandin synthesis, which may be due to its ability to bind nonsteroidal anti-inflammatory drugs (NSAIDs) by hydrogen bonding at their active site.

Formula: C₆H₄ClNO₂

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 157.55 g/mol

Ref: 3D-FC37673

2-Chloronicotinic acid

CAS: 2942-59-8

Formula: C₆H₄ClNO₂

Purity: 96%

Color and Shape: Solid

Molecular weight: 157.55

Ref: 10-F010748