CAS 2942328-06-3

LRRK2-IN-14

Formula: C₁₇H₁₈F₃N₅O₂

Synonyms:

• LRRK2-IN-14

LRRK2-IN-14

CAS: 2942328-06-3

LRRK2-IN-14 (Compound 8), an orally active inhibitor of LRRK2, exhibits an IC 50 of 6.3 nM against LRRK2(G2019S) cell activity and demonstrates inhibitory effects on hERG with an IC 50 of 22 μM. Additionally, LRRK2-IN-14 is permeable to the blood-brain barrier [1].

Formula: C₁₇H₁₈F₃N₅O₂

Color and Shape: Solid

Molecular weight: 381.35

Ref: TM-T86825