CAS 2946-39-6

8-Bromoadenosine

Description:

8-Bromoadenosine is a modified nucleoside that features a bromine atom substituted at the 8-position of the adenine base. This compound is characterized by its structural similarity to adenosine, which is a crucial component of nucleic acids and plays significant roles in cellular metabolism and signaling. The presence of the bromine atom can influence the compound's biological activity, potentially affecting its interactions with enzymes and receptors. 8-Bromoadenosine is often used in biochemical research to study adenosine receptors and their signaling pathways, as well as in the development of therapeutic agents. It is typically soluble in polar solvents, and its reactivity can be attributed to the presence of the bromine atom, which may participate in various chemical reactions. Additionally, this compound can exhibit unique pharmacological properties, making it a valuable tool in pharmacological studies. As with many chemical substances, proper handling and safety precautions are essential due to its potential biological effects.

Formula: C₁₀H₁₂BrN₅O₄

InChI: InChI=1S/C10H12BrN5O4/c11-10-15-4-7(12)13-2-14-8(4)16(10)9-6(19)5(18)3(1-17)20-9/h2-3,5-6,9,17-19H,1H2,(H2,12,13,14)/t3-,5-,6-,9-/m1/s1

InChI key: InChIKey=VJUPMOPLUQHMLE-UUOKFMHZSA-N

SMILES: BrC=1N(C=2C(N1)=C(N)N=CN2)[C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O

Synonyms:

• (2R,3R,4S,5R)-2-(6-Amino-8-Bromo-Purin-9-Yl)-5-Hydroxymethyl-Tetrahydro-Furan-3,4-Diol
• 6-Amino-8-Bromopurine Riboside
• 6-Amino-8-bromopurine riboside, 8-Bromoadenine-9-β-D-ribofuranoside
• 8-Bromo-Adenosine
• 8-Bromo-D-Adenosine
• 8-Bromoadenine-9-Beta-D-Ribofuranoside
• 8-Bromoadenosine, Hplc Purified, 98% Pure With Hplc Uv Chromatogram
• 8-bromo-9-pentofuranosyl-9H-purin-6-amine
• Adenosine, 8-bromo-
• NSC 79213
• 6-Amino-8-bromopurine riboside, 8-Bromoadenine-9-尾-D-ribofuranoside

Adenosine, 8-bromo-

CAS: 2946-39-6

Formula: C₁₀H₁₂BrN₅O₄

Purity: 97%

Color and Shape: Solid

Molecular weight: 346.1374

Ref: IN-DA002YG1

8-Bromoadenosine

CAS: 2946-39-6

8-Bromoadenosine

Purity: 98%

Molecular weight: 346.14g/mol

Ref: 54-OR1012091

8-Bromoadenosine

CAS: 2946-39-6

Formula: C₁₀H₁₂BrN₅O₄

Molecular weight: 346.15

Ref: 7W-GN5425

8-Bromoadenosine

CAS: 2946-39-6

8-Bromoadenosine is an adenosine derivative. 8-Br-Adenosine inhibitis mitochondrial membrane potential, cytoplasmic Ca²⁺ levels, and RNA and protein synthesis.

Formula: C₁₀H₁₂BrN₅O₄

Purity: 99.11%

Color and Shape: Solid

Molecular weight: 346.14

Ref: TM-TNU0791

8-Bromoadenosine

CAS: 2946-39-6

Formula: C₁₀H₁₂BrN₅O₄

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 346.14

Ref: 3B-B3795

8-Bromoadenosine

CAS: 2946-39-6

8-Bromoadenosine is a nucleotide that is structurally related to adenosine. It can be used as an inhibitor of guanine nucleotide-binding proteins and has shown biological properties in vitro. 8-Bromoadenosine has been shown to inhibit the mitochondrial membrane potential, cytosolic Ca2+, and the synthesis of RNA and protein. 8-Bromoadenosine also inhibits leukemia inhibitory factor (LIF) production by 3T3-L1 preadipocytes and induces apoptosis in T84 cells. The drug may be useful for the treatment of leukemia or obesity-related diseases such as diabetes mellitus type 2.

Formula: C₁₀H₁₂BrN₅O₄

Purity: Min. 95%

Color and Shape: Yellow Powder

Molecular weight: 346.14 g/mol

Ref: 3D-NB03414

(2R,3R,4S,5R)-2-(6-Amino-8-bromo-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol

CAS: 2946-39-6

Formula: C₁₀H₁₂BrN₅O₄

Purity: 97%

Color and Shape: Liquid, No data available.

Molecular weight: 346.141

Ref: 10-F242679

8-Bromo Adenosine

Controlled Product

CAS: 2946-39-6

Formula: C₁₀H₁₂BrN₅O₄

Color and Shape: Neat

Molecular weight: 346.14

Ref: TR-B679375