CAS 2949-22-6

Ethyl isocyanatoacetate

Description:

Ethyl isocyanatoacetate is an organic compound characterized by its isocyanate functional group and an ester moiety. It typically appears as a colorless to pale yellow liquid with a distinctive odor. The compound is known for its reactivity, particularly due to the presence of the isocyanate group, which can participate in nucleophilic addition reactions and can react with amines, alcohols, and other nucleophiles. Ethyl isocyanatoacetate is soluble in organic solvents such as ether and acetone but has limited solubility in water. It is often used in organic synthesis, particularly in the preparation of various pharmaceuticals and agrochemicals. Safety precautions are essential when handling this compound, as it can be toxic and irritating to the skin, eyes, and respiratory system. Proper storage in a cool, dry place away from incompatible materials is recommended to maintain its stability and prevent hazardous reactions.

Formula: C₅H₇NO₃

InChI: InChI=1S/C5H7NO3/c1-2-9-5(8)3-6-4-7/h2-3H2,1H3

InChI key: InChIKey=DUVOZUPPHBRJJO-UHFFFAOYSA-N

SMILES: C(CN=C=O)(OCC)=O

Synonyms:

• Acetic acid, 2-isocyanato-, ethyl ester
• Acetic acid, isocyanato-, ethyl ester
• Carbethoxymethyl isocyanate
• Ethoxycarbonylmethyl isocyanate
• Ethyl N-(oxomethylene)glycinate
• Glycine ethyl ester isocyanate
• Glycine, N-carbonyl-, ethyl ester
• Isocyanatoacetic acid ethyl ester
• NSC 56429
• NSC 6276
• ethyl N-(oxomethylidene)glycinate

Ethyl Isocyanatoacetate

CAS: 2949-22-6

Formula: C₅H₇NO₃

Purity: >97.0%(GC)

Color and Shape: Colorless to Almost colorless clear liquid

Molecular weight: 129.12

Ref: 3B-I0386

Ethyl isocyanatoacetate, 98%

CAS: 2949-22-6

6-(carboxymethylureido)-()-nicotine (CMUNic)was prepared by using ethyl isocyanatoacetate. Ethyl isocyanatoacetate has been used in the preparation of nicotine immunogen, ethyl 8-carbamoyl-4-oxo-3,4-dihydroimidazo[5,1-d]-1,2,3,5-tetrazin-3-ylacetate, imidazo[1,2-c]-quinazoline-2,5-(3H,6H)dione. Thi

Formula: C₅H₇NO₃

Purity: 98%

Color and Shape: Liquid, Clear colorless to pale yellow

Molecular weight: 129.12

Ref: 02-L10609

Acetic acid, 2-isocyanato-, ethyl ester

CAS: 2949-22-6

Formula: C₅H₇NO₃

Purity: 95%

Color and Shape: Liquid

Molecular weight: 129.1140

Ref: IN-DA002YKN

Ethyl isocyanatoacetate

CAS: 2949-22-6

Ethyl isocyanatoacetate

Purity: 98%

Color and Shape: Colourless Liquid

Molecular weight: 129.11g/mol

Ref: 54-OR30501

Ethyl Isocyanatoacetate

Controlled Product

CAS: 2949-22-6

Applications is a building block used in various chemial synthesis such in the preparation of 6-(carboxymethylureido)-(±)-nicotine (CMUNic), nicotine immunogen, and  imidazo[1,2-c]-quinazoline-2,5-(3H,6H)dione.
References Y Hieda et. al,: The Journal of pharmacology and experimental therapeutics, 283(3), undefined (1998-2-12); Papadopoulos EP.Journal of Heterocyclic Chemistry 18(3), 515-518,

Formula: C₅H₇NO₃

Color and Shape: Neat

Molecular weight: 129.11

Ref: TR-E678885

Ethyl isocyanatoacetate

CAS: 2949-22-6

Ethyl isocyanatoacetate (EICA) is a fatty acid that has been shown to have antimicrobial activity. It forms coordination complexes with malonic acid and fatty acids, which inhibit the synthesis of proteins by binding to the ribosomes. The antimicrobial properties of EICA are due to its ability to disrupt protein synthesis in gram-negative organisms. EICA also inhibits locomotor activity and levels of human liver enzymes. It has ether linkages as well as sulfonic acid groups, which make it more soluble in water than other fatty acids.
EICA is metabolized by hepatic lipase into methylmalonic acid and ethylmalonic acid, which can lead to metabolic disorders such as alkaptonuria.

Formula: C₅H₇NO₃

Purity: Min. 95%

Color and Shape: Liquid

Molecular weight: 129.12 g/mol

Ref: 3D-FE01975