CAS 2954-52-1

2,3-Dihydro-5-propyl-2-thioxo-4(1H)-pyrimidinone

Description:

2,3-Dihydro-5-propyl-2-thioxo-4(1H)-pyrimidinone, with the CAS number 2954-52-1, is a heterocyclic compound belonging to the pyrimidine family. This substance features a pyrimidinone core, characterized by a six-membered ring containing two nitrogen atoms and a carbonyl group, along with a thioxo group (a sulfur atom double-bonded to a carbon atom) that contributes to its reactivity and potential biological activity. The presence of a propyl group enhances its hydrophobic characteristics, which can influence its solubility and interaction with biological systems. This compound may exhibit various pharmacological properties, making it of interest in medicinal chemistry. Its structural features suggest potential applications in drug development, particularly in targeting specific biological pathways. However, detailed studies on its toxicity, stability, and specific applications are necessary to fully understand its utility in various fields, including pharmaceuticals and agrochemicals.

Formula: C₇H₁₀N₂OS

InChI: InChI=1S/C7H10N2OS/c1-2-3-5-4-8-7(11)9-6(5)10/h4H,2-3H2,1H3,(H2,8,9,10,11)

InChI key: InChIKey=RWJRFPUNLXBCML-UHFFFAOYSA-N

SMILES: C(CC)C=1C(=O)NC(=S)NC1

Synonyms:

• 2,3-Dihydro-5-propyl-2-thioxo-4(1H)-pyrimidinone
• 2-Thio-5-propyluracil
• 4(1H)-Pyrimidinone, 2,3-dihydro-5-propyl-2-thioxo-
• 5-propyl-2-thioxo-2,3-dihydropyrimidin-4(1H)-one
• Uracil, 5-propyl-2-thio-
• 5-Propyl-2-thiouracil

4(1H)-Pyrimidinone, 2,3-dihydro-5-propyl-2-thioxo-

CAS: 2954-52-1

Formula: C₇H₁₀N₂OS

Molecular weight: 170.2321

Ref: IN-DA002YPG

5-Propyl-2-thiouracil

CAS: 2954-52-1

Formula: C₇H₁₀N₂OS

Molecular weight: 170.23

Ref: 7W-GL5012

5-Propyl-2-thiouracil

CAS: 2954-52-1

5-Propyl-2-thiouracil (PTU) is a drug used in the treatment of various types of cancer. It is a chemical analogue of thiouracil, but has a different mechanism of action. PTU inhibits the production of tropomyosin, which leads to inhibition of transcriptional regulation and expression of protein genes. PTU also blocks the hydrogen bond between the amino acid glutamine and deoxyribose phosphate backbone, thereby inhibiting translation. Clinical studies have shown that PTU is effective in treating cardiac hypertrophy, renal proximal tubule cells and clinical nephropathy. The use of PTU as a chemotherapeutic agent for cancer treatment has been limited due to its toxicity to animals.

Formula: C₇H₁₀N₂OS

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 170.23 g/mol

Ref: 3D-FP08053