Description:P-tolyl trifluoromethanesulfonate, also known as p-tolyl triflate, is an organic compound characterized by the presence of a p-tolyl group (a para-substituted toluene) attached to a trifluoromethanesulfonate moiety. This compound is typically a colorless to pale yellow liquid and is known for its high reactivity, particularly as an electrophilic reagent in organic synthesis. The triflate group is a potent leaving group, making p-tolyl trifluoromethanesulfonate valuable in various nucleophilic substitution reactions. It is often used in the formation of carbon-carbon and carbon-heteroatom bonds, facilitating the synthesis of complex organic molecules. Additionally, the presence of trifluoromethyl groups enhances the compound's stability and solubility in polar solvents. Safety precautions should be observed when handling this compound, as it can be harmful if inhaled or absorbed through the skin. Overall, p-tolyl trifluoromethanesulfonate is a versatile reagent in synthetic organic chemistry, contributing to the development of pharmaceuticals and other fine chemicals.
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