CAS 29545-47-9

12-doxyl-stearic acid

Description:

12-Doxyl-stearic acid is a long-chain fatty acid derivative characterized by the presence of a nitroxide spin label at the 12th carbon position of the stearic acid molecule. This compound is primarily used in biophysical studies, particularly in the field of membrane biophysics, due to its ability to serve as a spin probe. The nitroxide group allows for electron paramagnetic resonance (EPR) spectroscopy, enabling researchers to investigate the dynamics and properties of lipid bilayers and membrane proteins. 12-Doxyl-stearic acid is typically soluble in organic solvents and exhibits amphiphilic properties, which means it can interact with both hydrophilic and hydrophobic environments. Its unique structure contributes to its utility in studying molecular interactions, phase transitions, and the fluidity of biological membranes. Additionally, the compound's stability and reactivity make it a valuable tool in various experimental setups, providing insights into the behavior of lipid systems under different conditions.

Formula: C₂₂H₄₂NO₄

InChI: InChI=1/C22H42NO4/c1-5-6-15-19(2)22(23(26)21(3,4)18-27-22)17-14-12-10-8-7-9-11-13-16-20(24)25/h19H,5-18H2,1-4H3,(H,24,25)

SMILES: CCCCC(C)C1(CCCCCCCCCCC(=O)O)N(C(C)(C)CO1)O

Synonyms:

• DOXYLstearicacid,95%
• 12-Doxylstearic Acid
• [2-(10-Carboxydecyl)-2-Hexyl-4,4-Dimethyl-1,3-Oxazolidin-3-Yl]Oxidanyl
• [2-(10-Carboxydecyl)-4,4-Dimethyl-2-(1-Methylpentyl)-1,3-Oxazolidin-3-Yl]Oxidanyl

12-doxyl Stearic Acid

CAS: 29545-47-9

Formula: C₂₂H₄₂NO₄

Molecular weight: 384.5732

Ref: IN-DA002YOW

12-doxyl Stearic Acid

CAS: 29545-47-9

12-Doxyl stearic acid, a derivative of stearic acid featuring a 4,4-dimethyl-3-oxazolinyloxy (DOXYL) group, functions as a hydrophobic spin label. This compound is prevalently utilized in research to investigate the molecular characteristics of membranes and hydrophobic proteins.

Formula: C₂₂H₄₂NO₄

Color and Shape: Solid

Molecular weight: 384.6

Ref: TM-T84394

12-Doxyl stearic acid

CAS: 29545-47-9

12-Doxyl stearic acid is a fatty acid that inhibits the vasoactive intestinal peptide (VIP). The inhibitory effect of 12-Doxyl stearic acid on VIP was demonstrated by incubating the cells with this fatty acid and measuring the change in mitochondrial Ca2+ concentration. This inhibition was shown to be due to the inhibition of fatty acids and not an effect on Ca2+ ion channels. Fatty acids are important for normal cellular function, such as maintaining membrane fluidity and aiding in signal transduction. 12-Doxyl stearic acid has been shown to inhibit the production of cardiac fatty acids and may be useful in treating cardiac disorders. 12-Doxyl stearic acid also has a fluorescence probe that can be used to study how cells react to different conditions, such as changes in water vapor or pH levels.

Formula: C₂₂H₄₂NO₄

Purity: Min. 95%

Color and Shape: Yellow Clear Liquid

Molecular weight: 384.57 g/mol

Ref: 3D-FD22610