CAS 2958-04-5

2-{[(3alpha,5beta,6alpha)-3,6-dihydroxy-24-oxocholan-24-yl]amino}ethanesulfonic acid

Description:

2-{[(3alpha,5beta,6alpha)-3,6-dihydroxy-24-oxocholan-24-yl]amino}ethanesulfonic acid, commonly known as tauroursodeoxycholic acid (TUDCA), is a bile acid derivative with notable biochemical properties. It is characterized by its amphipathic nature, which allows it to interact with both hydrophilic and hydrophobic environments. TUDCA plays a significant role in cellular processes, including the regulation of apoptosis and the promotion of cell survival, particularly in liver cells. Its structure features a steroid backbone with hydroxyl groups that enhance its solubility in water. The sulfonic acid group contributes to its acidic properties, making it a zwitterionic compound at physiological pH. TUDCA is often studied for its potential therapeutic effects in liver diseases and neurodegenerative disorders due to its ability to mitigate endoplasmic reticulum stress. Additionally, it has been investigated for its role in improving insulin sensitivity and its protective effects against various forms of cellular stress. Overall, TUDCA is a compound of interest in both clinical and biochemical research.

Formula: C₂₆H₄₅NO₆S

InChI: InChI=1/C26H45NO6S/c1-16(4-7-24(30)27-12-13-34(31,32)33)19-5-6-20-18-15-23(29)22-14-17(28)8-10-26(22,3)21(18)9-11-25(19,20)2/h16-23,28-29H,4-15H2,1-3H3,(H,27,30)(H,31,32,33)/t16-,17-,18+,19-,20+,21+,22+,23+,25-,26-/m1/s1

2-((R)-4-((3R,5R,6S,8S,9S,10R,13R,14S,17R)-3,6-Dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanamido)ethane-1-sulfonic acid

CAS: 2958-04-5

2-((R)-4-((3R,5R,6S,8S,9S,10R,13R,14S,17R)-3,6-Dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanamido)ethane-1-sulfonic acid

Purity: 98%

Molecular weight: 499.71g/mol

Ref: 54-OR1073884

Taurohyodeoxycholic acid

CAS: 2958-04-5

Taurohyodeoxycholic acid (THDCA) is a bile acid.THDCA reduces TNF-α and IL-6 and CD36 and up-regulating CYP7B1 and down-regulating CYP7A1 in HCC liver.

Formula: C₂₆H₄₅NO₆S

Purity: 99.38%

Color and Shape: Solid

Molecular weight: 499.7

Ref: TM-T37770

Taurohyodeoxycholic Acid-d4 Sodium salt

CAS: 2958-04-5

Formula: C₂₆H₄₀D₄NO₆S·Na

Molecular weight: 502.72 22.99

Ref: 4Z-C-57104

Taurohyodeoxycholic Acid-13C2 Sodium Salt

CAS: 2958-04-5

Formula: C₂₄₁₃C₂₄₄NO₆S·Na

Molecular weight: 500.68 22.99

Ref: 4Z-C-57105

Taurohyodeoxycholic Acid

CAS: 2958-04-5

Formula: C₂₆H₄₅NO₆S

Molecular weight: 499.71

Ref: 4Z-C-5751

Taurohyodeoxycholic Acid

Controlled Product

CAS: 2958-04-5

Applications A bile acid which stimulates the flow of bile salts, for potential treatment of Irritable Bile Syndrome.
References Gnewuch, C., et al.: World J. Gastroenterol., 15, 3134 (2009), Yu, B., et al.: J. Nat. Prod., 72, 24 (2009), Lim, S., et al.: Int. J. Cancer, 126, 1582 (2010),

Formula: C₂₆H₄₅NO₆S

Color and Shape: Neat

Molecular weight: 499.70

Ref: TR-T007900

Taurohyodeoxycholic Acid-d4 Sodium Salt

Controlled Product

CAS: 2958-04-5

Applications Unlabeled Taurohyodeoxycholic Acid (T007900) is a bile acid which stimulates the flow of bile salts, for potential treatment of Irritable Bile Syndrome.
References Gnewuch, C., et al.: World J. Gastroenterol., 15, 3134 (2009), Yu, B., et al.: J. Nat. Prod., 72, 24 (2009), Lim, S., et al.: Int. J. Cancer, 126, 1582 (2010),

Formula: C₂₆H₄₁D₄NO₆S•xNa

Color and Shape: Neat

Molecular weight: 503.732299

Ref: TR-T007902