CAS 29632-74-4

2-Fluoro-4-iodoaniline

Description:

2-Fluoro-4-iodoaniline is an organic compound characterized by the presence of both fluorine and iodine substituents on an aniline structure. It features a fluorine atom at the ortho position (2-position) and an iodine atom at the para position (4-position) relative to the amino group (-NH2) on the benzene ring. This compound is typically a solid at room temperature and may exhibit a pale color. It is known for its potential applications in pharmaceuticals, agrochemicals, and as an intermediate in organic synthesis. The presence of both halogens can influence its reactivity, making it a useful building block in various chemical reactions, including nucleophilic substitutions and coupling reactions. Additionally, the compound's properties, such as solubility and melting point, can be affected by the electron-withdrawing nature of the halogen substituents. Safety precautions should be taken when handling this compound, as it may pose health risks, and proper disposal methods should be followed due to its potential environmental impact.

Formula: C₆H₅FIN

InChI: InChI=1/C6H5FIN/c7-5-2-1-4(8)3-6(5)9/h1-3H,9H2

InChI key: InChIKey=CUMTUBVTKOYYOU-UHFFFAOYSA-N

SMILES: FC1=C(N)C=CC(I)=C1

Synonyms:

• 1-(2-Chloro-5-Fluorophenyl)Ethanone
• 2-Fluoro-4-Iodo-Phenylamine
• 2-Fluoro-4-Iodobenzenamine
• 2-Fluoro-4-iodophenylamine
• 2-Fluoro-5-Iodo-Aniline
• 4-Iodo-2-fluoroaniline
• Aniline, 2-fluoro-4-iodo-
• Benzenamine, 2-fluoro-4-iodo-
• NSC 146507
• 2-Fluoro-4-iodoaniline
• 2-Fluoro-4-iodoaniline 98%
• 2-Fluoro-4-iodoaniline98%

2-Fluoro-4-iodoaniline

CAS: 29632-74-4

Formula: C₆H₅FIN

Purity: >98.0%(GC)

Color and Shape: White to Gray to Brown powder to crystal

Molecular weight: 237.02

Ref: 3B-F0417

2-Fluoro-4-iodoaniline, 99%

CAS: 29632-74-4

2-Fluoro-4-iodoaniline is widely used in the pharmaceutical, chemical and food industries as a fundamental building block to create a variety of important compounds. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label

Formula: C₆H₅FIN

Purity: 99%

Color and Shape: Pale cream to cream to pale brown to gray, Powder

Molecular weight: 237.02

Ref: 02-B22450

Benzenamine, 2-fluoro-4-iodo-

CAS: 29632-74-4

Formula: C₆H₅FIN

Purity: 98%

Color and Shape: Solid

Molecular weight: 237.0135

Ref: IN-DA002YXV

2-Fluoro-4-iodoaniline, min. 98%

CAS: 29632-74-4

Formula: FC₆H₃(I)NH₂

Purity: min. 98%

Color and Shape: White to brown, to include purple solid

Molecular weight: 237.01

Ref: 08-09-0013

2-Fluoro-4-iodoaniline

CAS: 29632-74-4

2-Fluoro-4-iodoaniline

Formula: C₆H₅FIN

Purity: 98%

Color and Shape: light grey to pale brown solid

Molecular weight: 237.01g/mol

Ref: 54-PC3759E

2-Fluoro-4-iodoaniline

CAS: 29632-74-4

Formula: C₆H₅FIN

Purity: 97%

Color and Shape: Solid

Molecular weight: 237.016

Ref: 10-F010682

2-Fluoro-4-iodoaniline

Controlled Product

CAS: 29632-74-4

Applications 2-Fluoro-4-iodoaniline is widely used in the pharmaceutical, chemical and food industries as a fundamental building block to create a variety of important compounds. 2-Fluoro-4-iodoaniline is mostly known as a moiety of TAK-733, a selective inhibitor of mitogen-activated or extracellular signal-regulated protein kinase kinase 2 (MEK2).
References Dong, Q., et al.: Bioorg. Med. Chem. Lett., 21, 1315 (2011); Heald, R., et al.: J. Med. Chem., 55, 4594 (2012)

Formula: C₆H₅FIN

Color and Shape: Neat

Molecular weight: 237.01

Ref: TR-F591985

2-Fluoro-4-iodoaniline

CAS: 29632-74-4

Formula: FC₆H₃(I)NH₂

Purity: 98.0 min. %

Color and Shape: White to brown, to include purple solid

Molecular weight: 237.01

Ref: 08-F053