CAS 29678-81-7

(R)-2-Hydroxy-4-phenylbutyric acid

Description:

(R)-2-Hydroxy-4-phenylbutyric acid, also known as (R)-HPBA, is a chiral compound characterized by its hydroxyl and carboxylic acid functional groups. It features a butyric acid backbone with a phenyl group attached to the fourth carbon, contributing to its unique properties. This compound is typically a white to off-white solid at room temperature and is soluble in polar solvents such as water and alcohols, owing to the presence of the hydroxyl and carboxylic acid groups. (R)-HPBA is of interest in pharmaceutical research, particularly for its potential therapeutic applications, including anti-inflammatory and analgesic effects. The chirality of the molecule is significant, as the (R)-enantiomer may exhibit different biological activity compared to its (S)-counterpart. Its synthesis often involves asymmetric synthesis techniques to ensure the desired stereochemistry. Additionally, (R)-HPBA can serve as a building block in organic synthesis, facilitating the development of more complex molecules in medicinal chemistry.

Formula: C₁₀H₁₂O₃

InChI: InChI=1/C10H12O3/c11-9(10(12)13)7-6-8-4-2-1-3-5-8/h1-5,9,11H,6-7H2,(H,12,13)/t9-/m1/s1

InChI key: InChIKey=JNJCEALGCZSIGB-SECBINFHSA-N

SMILES: C(C[C@H](C(O)=O)O)C1=CC=CC=C1

Synonyms:

• (2R)-2-hydroxy-4-phenylbutanoic acid
• (R)-2-Hydroxy-4-Phenyl Butyric Acid
• (R)-2-Hydroxy-4-phenylbutanoic Acid
• (r)-2-Hydroxy-4-phenylbutyricacid
• (αR)-α-Hydroxybenzenebutanoic acid
• <span class="text-smallcaps">D</span>-(-)-Benzyllactic acid
• Benzenebutanoic acid, α-hydroxy-, (R)-
• Benzenebutanoic acid, α-hydroxy-, (αR)-
• Butyric acid, 2-hydroxy-4-phenyl-, <span class="text-smallcaps">D</span>-(-)-
• Butyric acid, 2-hydroxy-4-phenyl-, D-(-)-
• D-(-)-Benzyllactic acid
• R(-)-2-HYDROXY-4-PHENYL-BUTYIC ACID
• (R)-HPBA
• (2R)-2-Hydroxy-4-phenylbutyric acid
• 2-hydroxy-4-phenylbutanoic acid2-hydroxy-4-phenylbutyric aci
• (R)-2-Hydroxy-4-pheylbutanoic Acid
• (R)-(-)-2-HYDROXY-4-PHENYLBUTYRIC ACID
• (R)-2-HYDROXY-4-PHENYLBUTYRIC ACID

Benzenebutanoic acid, α-hydroxy-, (αR)-

CAS: 29678-81-7

Formula: C₁₀H₁₂O₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 180.2005

Ref: IN-DA002Z30

(R)-(-)-2-Hydroxy-4-phenylbutyric acid

CAS: 29678-81-7

(R)-(-)-2-Hydroxy-4-phenylbutyric acid

Purity: 98%

Molecular weight: 180.20g/mol

Ref: 54-OR307154

(R)-2-Hydroxy-4-phenylbutyric Acid

CAS: 29678-81-7

Formula: C₁₀H₁₂O₃

Purity: >97.0%(GC)(T)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 180.20

Ref: 3B-H1338

(R)-2-Hydroxy-4-phenylbutyric acid

CAS: 29678-81-7

Formula: C₁₀H₁₂O₃

Purity: 98%

Color and Shape: Solid, White powder

Molecular weight: 180.203

Ref: 10-F011769

(R)-2-Hydroxy-4-phenylbutanoic acid

CAS: 29678-81-7

(R)-2-Hydroxy-4-phenylbutanoic acid is an ester compound that is produced by the conversion of (S)-malic acid to its enantiomer. This reaction is catalyzed by a phosphoric acid esterase. The kinetic, immobilization, and transfer mechanisms have been characterized. The solubilized form of the enzyme was found to be more active than the crystalline form. Enzyme inhibitors such as hydrogen chloride and hydrochloric acid were also investigated in order to determine their effect on the reaction rate and product distribution. A structural formula for (R)-2-Hydroxy-4-phenylbutanoic acid was determined using nuclear magnetic resonance spectroscopy and mass spectrometry, revealing a dinucleotide phosphate as a possible intermediate in the synthesis pathway.

Formula: C₁₀H₁₂O₃

Purity: Min. 95%

Molecular weight: 180.2 g/mol

Ref: 3D-FH140634