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CAS 296790-70-0

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  • IL-6-IN-2
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    IL-6-IN-2

    CAS:
    IL-6-IN-2 (Compound 15) is an inhibitor of the interaction between IL-6 and IL-6R proteins. The compound's binding free energy (∆G) is −36.50 kcal/mol. In its binding with IL-6, the contributions from Lys66, Phe74, Gln175, Ser176, and Arg179 are -1.10, -8.68, -6.91, -3.69, and -1.72 kcal/mol, respectively. IL-6-IN-2 exhibits low gastrointestinal (GI) absorption rates.
    Formula:C26H24N4O3
    Color and Shape:Solid
    Molecular weight:440.49

    Ref: TM-T212342

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