CAS 29699-89-6

4-Nitro-sulfamethoxazole

Description:

4-Nitro-sulfamethoxazole is a sulfonamide antibiotic that belongs to the class of sulfa drugs, which are known for their antibacterial properties. It is characterized by the presence of a nitro group and a sulfonamide functional group, which contribute to its mechanism of action by inhibiting bacterial folic acid synthesis. This compound typically appears as a crystalline solid and is soluble in organic solvents but has limited solubility in water. Its chemical structure allows it to effectively target a range of Gram-positive and Gram-negative bacteria, making it useful in treating various infections. The compound is often used in combination with other antibiotics to enhance its efficacy and reduce the risk of resistance development. Additionally, 4-Nitro-sulfamethoxazole may exhibit side effects common to sulfonamides, such as allergic reactions or gastrointestinal disturbances. As with all antibiotics, its use should be guided by susceptibility testing to ensure effectiveness against specific pathogens.

Formula: C₁₀H₉N₃O₅S

InChI: InChI=1S/C10H9N3O5S/c1-7-6-10(11-18-7)12-19(16,17)9-4-2-8(3-5-9)13(14)15/h2-6H,1H3,(H,11,12)

InChI key: InChIKey=XHJLDAHBWWMCRZ-UHFFFAOYSA-N

SMILES: N(S(=O)(=O)C1=CC=C(N(=O)=O)C=C1)C2=NOC(C)=C2

Synonyms:

• 4-Nitro-sulfamethoxazole
• Benzenesulfonamide, N-(5-methyl-3-isoxazolyl)-4-nitro-
• Benzenesulfonamide, N-(5-methyl-3-isoxazolyl)-p-nitro-
• N-(5-Methyl-3-isoxazolyl)-4-nitrobenzenesulfonamide
• N-(5-Methylisoxazol-3-yl)-4-nitrobenzenesulfonamide
• Nitrosulfamethoxazole
• N-(5-Methyl-1,2-oxazol-3-yl)-4-nitrobenzenesulfonamide

Sulfamethoxazole-NO

CAS: 29699-89-6

Sulfamethoxazole-NO (SMX-NO) is a SMX-NO derivative that is a major immunogen for sulfonamide hypersensitivity reactions, is cytotoxic, and is immunogenic in rodents.

Formula: C₁₀H₉N₃O₅S

Purity: 99.99%

Color and Shape: Soild

Molecular weight: 283.26

Ref: TM-T200416

Benzenesulfonamide, N-(5-methyl-3-isoxazolyl)-4-nitro-

CAS: 29699-89-6

Formula: C₁₀H₉N₃O₅S

Purity: 98%

Color and Shape: Solid

Molecular weight: 283.2606

Ref: IN-DA002Z4I

Sulfamethoxazole Impurity 3

CAS: 29699-89-6

Formula: C₁₀H₉N₃O₅S

Molecular weight: 283.26

Ref: 4Z-S-5012

Sulfamethoxazole Impurity 3-d4

CAS: 29699-89-6

Formula: C₁₀H₅D₄N₃O₅S

Molecular weight: 287.28

Ref: 4Z-S-5013

Sulfamethoxazole-NO

CAS: 29699-89-6

Sulfamethoxazole-NO

Purity: ≥98%

Molecular weight: 283.26g/mol

Ref: 54-BUP12108

4-Nitro Sulfamethoxazole

Controlled Product

CAS: 29699-89-6

Applications A Sulfamethoxazole metabolite.
References Gill, H., et al.: Br. J. Clin. Pharmacol., 42, 347 (1996), Winter, H., et al.: Clin. Pharmacol. Ther., 76, 579 (2004), Vyas, P., et al.: Biochem. Pharmacol., 70, 275 (2005), Vyas, P., et al.: Drug Metab. Dispos., 34, 16 (2006),

Formula: C₁₀H₉N₃O₅S

Color and Shape: Light Brown

Molecular weight: 283.26

Ref: TR-N549000

4-Nitro-sulfamethoxazole

CAS: 29699-89-6

Purity: 98%

Molecular weight: 283.03

Ref: 10-F553566

4-Nitro-sulfamethoxazole

CAS: 29699-89-6

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Formula: C₁₀H₉N₃O₅S

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 283.26 g/mol

Ref: 3D-FN182590