CAS 29702-43-0

2-Fluoro-2-deoxy-D-glucose

Description:

2-Fluoro-2-deoxy-D-glucose (FDG) is a synthetic analog of glucose, where the hydroxyl group at the second carbon is replaced by a fluorine atom. This modification imparts unique properties that make FDG particularly valuable in medical imaging, especially in positron emission tomography (PET) scans. The presence of the fluorine atom allows for the radiolabeling of the molecule, enabling visualization of metabolic processes in vivo. FDG is a white to off-white crystalline powder that is soluble in water, and it is typically administered in a sterile form for diagnostic purposes. Biochemically, FDG is taken up by cells in a manner similar to glucose, but it is not metabolized further due to the absence of a hydroxyl group, leading to its accumulation in tissues with high glucose metabolism, such as tumors. This characteristic makes FDG a crucial tool in oncology for detecting and monitoring cancer. Additionally, it has applications in research related to glucose metabolism and various metabolic disorders.

Formula: C₆H₁₁FO₅

InChI: InChI=1S/C6H11FO5/c7-3(1-8)5(11)6(12)4(10)2-9/h1,3-6,9-12H,2H2/t3-,4+,5+,6+/m0/s1

InChI key: InChIKey=AOYNUTHNTBLRMT-SLPGGIOYSA-N

SMILES: [C@H]([C@@H]([C@@H](CO)O)O)([C@H](C=O)F)O

Synonyms:

• 2-Deoxy-2-Fluorohexopyranose
• 2-Deoxy-2-fluoro-<span class="text-smallcaps">D</span>-glucopyranose
• 2-Deoxy-2-fluoro-<span class="text-smallcaps">D</span>-glucose
• 2-Deoxy-2-fluoro-D-glucose
• 2-Deoxy-2-fluoroglucose
• 2-Deoxy-fluoro-glucose
• 2-Fluoro-2-deoxy-<span class="text-smallcaps">D</span>-glucose
• 2-Fluorodeoxyglucose
• 2-fluoro-2-deoxy-D-glucose
• 2-fluoro-2-deoxy-D-glucose, mixture of anomers
• <span class="text-smallcaps">D</span>-Glucose, 2-deoxy-2-fluoro-
• D-Glucopyranose, 2-deoxy-2-fluoro-FDG
• Fluorodeoxyglucose

2-Deoxy-2-fluoro-D-glucopyranose

CAS: 29702-43-0

Formula: C₆H₁₁FO₅

Purity: >98.0%(GC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 182.15

Ref: 3B-D3023

Fludeoxyglucose

CAS: 29702-43-0

Heterocyclic compounds with oxygen hetero-atom(s) only, nesoi

Formula: C₆H₁₁FO₅

Color and Shape: White Powder

Molecular weight: 182.05905

Ref: 45-1272907

2-Deoxy-2-fluoro-D-glucopyranose

CAS: 29702-43-0

Formula: C₆H₁₁FO₅

Purity: 98%

Color and Shape: Solid

Molecular weight: 182.1469

Ref: IN-DA002Z5B

2-deoxy-2-fluoro-D-Glucose

CAS: 29702-43-0

2-FG, a glucose derivative with anticancer properties, inhibits 143B osteosarcoma cells at 6-24 mM under varying oxygen levels.

Formula: C₆H₁₁FO₅

Color and Shape: Solid

Molecular weight: 182.15

Ref: TM-T35682

2-Deoxy-2-fluoro-D-glucose

CAS: 29702-43-0

Molecular weight: 182.15

Ref: 7W-GC7411

2-Deoxy-2-fluoro-D-glucose

CAS: 29702-43-0

2-Deoxy-2-fluoro-D-glucose

Formula: C₆H₁₁FO₅

Purity: 97%

Color and Shape: white solid

Molecular weight: 182.15g/mol

Ref: 54-BID1009

2-Deoxy-2-fluoro-D-glucopyranose

CAS: 29702-43-0

2-Deoxy-2-fluoro-D-glucopyranose

Purity: 98%

Color and Shape: White Solid

Molecular weight: 182.15g/mol

Ref: 54-BICL4075

2-Deoxy-2-fluoro-D-glucose

CAS: 29702-43-0

2-Deoxy-2-fluoro-D-glucose

Formula: C₆H₁₁FO₅

Purity: By hplc: 99.1% (Typical Value in Batch COA)

Color and Shape: white powder

Molecular weight: 182.15g/mol

Ref: 54-PC7306

2-Deoxy-2-fluoro-D-glucose

Controlled Product

CAS: 29702-43-0

Stability Hygroscopic
Applications A substrate of hexokinase isozymes.

Formula: C₆H₁₁FO₅

Color and Shape: White Solid

Molecular weight: 182.15

Ref: TR-D234500

2-Deoxy-2-fluoro-D-glucose

CAS: 29702-43-0

Inhibitor of hexokinase isozymes and cellular glycosylation

Formula: C₆H₁₁FO₅

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 182.15 g/mol

Ref: 3D-MD03509

(2R,3S,4R,5R)-2-FLUORO-3,4,5,6-TETRAHYDROXYHEXANAL

CAS: 29702-43-0

Purity: 98%

Molecular weight: 182.1470032

Ref: 10-F826920

2-Fluoro-2-deoxy-D-glucose

CAS: 29702-43-0

Formula: C₆H₁₁FO₅

Purity: 95.0%

Color and Shape: Solid

Molecular weight: 182.147

Ref: 10-F009448

2-Deoxy-2-fluoro-D-glucose-13C6

Controlled Product

CAS: 29702-43-0

Applications 2-Deoxy-2-fluoro-D-glucose-13C6 is the isotope labelled analogue of 2-Deoxy-3-fluoro-D-glucose (D234500), a substrate of hexokinase isozymes.
References Cheyne, R.W., et al.: Nuc. Med. Biol., 38, 339 (2011);

Formula: C₆H₁₁FO₅

Color and Shape: Neat

Molecular weight: 188.1

Ref: TR-D234503