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CAS 29706-84-1

:

3′-Azido-3′-deoxy-5′-O-(triphenylmethyl)thymidine

Description:
3′-Azido-3′-deoxy-5′-O-(triphenylmethyl)thymidine, with the CAS number 29706-84-1, is a nucleoside analog that features an azido group at the 3′ position and a triphenylmethyl (Trityl) protecting group at the 5′ position. This compound is characterized by its structural modifications that enhance its stability and bioactivity, making it of interest in medicinal chemistry, particularly in antiviral research. The azido group is known for its potential to be converted into reactive species, which can interfere with viral replication processes. The triphenylmethyl group serves as a protective moiety, allowing for selective reactions and facilitating further chemical modifications. This compound is typically used in the synthesis of other nucleoside derivatives and has implications in the development of antiviral therapies, especially against retroviruses like HIV. Its properties include solubility in organic solvents and stability under certain conditions, although it may be sensitive to light and moisture. Overall, 3′-Azido-3′-deoxy-5′-O-(triphenylmethyl)thymidine represents a significant tool in the field of nucleoside chemistry and drug development.
Formula:C29H27N5O4
InChI:InChI=1S/C29H27N5O4/c1-20-18-34(28(36)31-27(20)35)26-17-24(32-33-30)25(38-26)19-37-29(21-11-5-2-6-12-21,22-13-7-3-8-14-22)23-15-9-4-10-16-23/h2-16,18,24-26H,17,19H2,1H3,(H,31,35,36)/t24-,25+,26+/m0/s1
InChI key:InChIKey=AZPSSDWPMSICSH-JIMJEQGWSA-N
SMILES:C(OC[C@@H]1[C@@H](N=[N+]=[N-])C[C@@H](O1)N2C(=O)NC(=O)C(C)=C2)(C3=CC=CC=C3)(C4=CC=CC=C4)C5=CC=CC=C5
Synonyms:
  • 3'-Azido-3'-deoxy-5'-O-tritylthymidine
  • 3-Azido-3-Deoxy-5-O-Triphenylmethylthymidine
  • 3′-Azido-3′-deoxy-5′-O-(triphenylmethyl)thymidine
  • Thymidine, 3′-azido-3′-deoxy-5′-O-trityl-
  • Thymidine,3'-azido-3'-deoxy-5'-O-trityl- (8CI)
  • Thymidine, 3′-azido-3′-deoxy-5′-O-(triphenylmethyl)-
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