CAS 29745-04-8
:Norcantharidin
Description:
Norcantharidin is a chemical compound derived from cantharidin, which is a natural product obtained from blister beetles. It is classified as a terpenoid and is known for its potential medicinal properties, particularly in cancer research. Norcantharidin exhibits characteristics such as being a colorless to pale yellow solid at room temperature, with a relatively low solubility in water but higher solubility in organic solvents. The compound has been studied for its ability to inhibit tumor growth and induce apoptosis in cancer cells, making it a subject of interest in pharmacological studies. Its mechanism of action involves the disruption of cellular processes, particularly those related to cell division and survival. Additionally, norcantharidin has been noted for its potential anti-inflammatory and antiviral properties. However, it is essential to handle this compound with care due to its toxicity and potential side effects. As research continues, norcantharidin may offer insights into novel therapeutic approaches for various diseases.
Formula:C8H8O4
InChI:InChI=1/C8H8O4/c9-7-5-3-1-2-4(11-3)6(5)8(10)12-7/h3-6H,1-2H2/t3-,4+,5-,6+
InChI key:InChIKey=JAABVEXCGCXWRR-FBXFSONDNA-N
SMILES:O=C1[C@]2([C@]([C@]3(O[C@@]2(CC3)[H])[H])(C(=O)O1)[H])[H]
Synonyms:- (3aR,4S,7R,7aS)-hexahydro-4,7-epoxy-2-benzofuran-1,3-dione
- (3aR,4S,7R,7aS)-rel-Hexahydro-4,7-epoxyisobenzofuran-1,3-dione
- 4,10-Dioxatricyclo[5.2.1.0(2,6)]decane-3,5-dione
- 4,7-Epoxyisobenzofuran-1,3-dione, hexahydro-, (3aR,4S,7R,7aS)-rel-
- 4,7-Epoxyisobenzofuran-1,3-dione, hexahydro-, (3aα,4β,7β,7aα)-
- 7-Oxabicyclo[2.2.1]heptane-2,3-dicarboxylic Anhydride
- 7-Oxabicyclo[2.2.1]heptane-2,3-dicarboxylic anhydride, exo-
- 7-Oxabicyclo[2.2.1]heptane-exo-cis-2,3-dicarboxylic anhydride
- Demehylcantharidin
- Demethylcantharidin
- Exo-7-Oxabicyclo[2.2.1]Heptane-2,3-Dicarboxylic Anhydride
- Hexahydro-4,7-Epoxy-2-Benzofuran-1,3-Dione
- Isocantharidin
- NSC 59023
- exo-7-Oxabicyclo[2.2.1]heptane-2,3-dicarboxylic acid anhydride
- See more synonyms
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Found 10 products.
Norcantharidin
CAS:Formula:C8H8O4Purity:>98.0%(GC)(T)Color and Shape:White to Almost white powder to crystalMolecular weight:168.15Norcantharidin, mixture of endo/exo
CAS:Formula:C8H8O4Purity:97%Color and Shape:SolidMolecular weight:168.1467Norcantharidin
CAS:Formula:C8H8O4Purity:(Titration) ≥ 98.0%Color and Shape:White to almost white powder or crystalsMolecular weight:168.15(±)-Norcantharidin
CAS:<p>(±)-Norcantharidin (Endothall anhydride) is a synthetic anticancer compound which is a dual inhibitor for c-Met and EGFR in human colon cancers.</p>Formula:C8H8O4Purity:99.43% - ≥98%Color and Shape:SolidMolecular weight:168.15Norcantharidin
CAS:Controlled Product<p>Stability Moisture Sensitive<br>Applications Norcantharidin is a potential antitumor agent.<br></p>Formula:C8H8O4Color and Shape:NeatMolecular weight:168.157-Oxabicyclo[2.2.1]heptane-2,3-dicarboxylic Anhydride
CAS:Formula:C8H8O4Purity:95.0%Color and Shape:SolidMolecular weight:168.148Norcantharidin
CAS:<p>Norcantharidin is an antitumor drug that belongs to the group of pyrazole derivatives. It has shown significant cytotoxicity against human cancer cells in vitro and in vivo. Norcantharidin induces apoptosis by binding to DNA, inhibiting RNA polymerase activity, and blocking the synthesis of proteins needed for cell division. Norcantharidin also inhibits growth of the tumor by inducing differentiation of epithelial mesenchymal cells into fibroblasts. This drug has been shown to induce apoptosis in hl-60 cells at low doses (10 µM) and has a significant cytotoxicity against HL-60 cells at high doses (>10 µM).</p>Formula:C8H8O4Purity:Min. 95%Molecular weight:168.15 g/mol
![7-Oxabicyclo[2.2.1]heptane-2,3-dicarboxylic Anhydride](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F10%2Fthumb%2FF341906.jpg&w=3840&q=75)
