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CAS 2978623-09-3

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  • PD-L1/VISTA-IN-1

    CAS:
    <p>PD-L1/VISTA-IN-1 (Compound P17) is an orally active dual inhibitor targeting PD-L1 and VISTA. It effectively hinders the PD-1/PD-L1 interaction (IC50: 0.1492 μM) and the VISTA pathway (KD: 0.2723 μM), leading to the reactivation of T cells. Additionally, PD-L1/VISTA-IN-1 exhibits antitumor activity.</p>
    Formula:C22H24N4O4
    Color and Shape:Solid
    Molecular weight:408.45