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CAS 2983036-90-2

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Thalidomide-NH-amido-PEG2-C2-NH2

Description:
Thalidomide-NH-amido-PEG2-C2-NH2 is a synthetic compound that combines elements of thalidomide, a well-known drug with immunomodulatory and anti-inflammatory properties, with a polyethylene glycol (PEG) moiety. The presence of the PEG chain enhances the solubility and bioavailability of the compound, potentially improving its pharmacokinetic profile. The amido and amine functional groups suggest that the compound may engage in hydrogen bonding, which can influence its interaction with biological targets. This compound is of interest in medicinal chemistry, particularly for its potential therapeutic applications in conditions such as cancer and autoimmune diseases. However, due to the historical context of thalidomide, which was associated with severe teratogenic effects, any derivatives must be carefully evaluated for safety and efficacy. The specific characteristics, such as melting point, solubility, and stability, would depend on the detailed molecular structure and should be determined through experimental studies. As with any novel compound, thorough research and clinical testing are essential to understand its full biological implications.
Synonyms:
  • Thalidomide-NH-amido-PEG2-C2-NH2
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