CAS 29836-40-6

Tremulacin

Description:

Tremulacin is a chemical compound classified as a secondary metabolite, primarily derived from certain fungi, particularly those in the genus *Inonotus*. It is known for its potential biological activities, including antimicrobial and anti-inflammatory properties. The compound has garnered interest in pharmacological research due to its ability to interact with various biological targets, which may lead to therapeutic applications. Tremulacin is characterized by its complex molecular structure, which includes multiple functional groups that contribute to its reactivity and biological effects. Its solubility properties can vary, influencing its bioavailability and efficacy in biological systems. Additionally, studies have indicated that tremulacin may exhibit cytotoxic effects against certain cancer cell lines, making it a subject of interest in cancer research. However, further studies are necessary to fully elucidate its mechanisms of action and potential applications in medicine. As with many natural products, the extraction and purification processes can significantly affect the yield and activity of tremulacin, highlighting the importance of careful methodological approaches in research.

Formula: C₂₇H₂₈O₁₁

InChI: InChI=1S/C27H28O11/c28-14-19-21(30)22(31)23(38-24(32)16-8-2-1-3-9-16)25(37-19)36-18-11-5-4-10-17(18)15-35-26(33)27(34)13-7-6-12-20(27)29/h1-5,7-11,13,19,21-23,25,28,30-31,34H,6,12,14-15H2/t19-,21-,22+,23-,25-,27+/m1/s1

InChI key: InChIKey=RCKCYCDBDYUIGM-OBZVFWKUSA-N

SMILES: O([C@H]1[C@H](OC(=O)C2=CC=CC=C2)[C@@H](O)[C@H](O)[C@@H](CO)O1)C3=C(COC(=O)[C@@]4(O)C(=O)CCC=C4)C=CC=C3

Synonyms:

• 2-cyclohexene-1-carboxylic acid, 1-hydroxy-6-oxo-, [2-[(2-O-benzoyl-beta-D-glucopyranosyl)oxy]phenyl]methyl ester
• Tremulacin
• β-<span class="text-smallcaps">D</span>-Glucopyranoside, 2-[[[[(1S)-1-hydroxy-6-oxo-2-cyclohexen-1-yl]carbonyl]oxy]methyl]phenyl, 2-benzoate
• 2-[(2-O-Benzoyl-beta-D-glucopyranosyl)oxy]benzyl 1-hydroxy-6-oxocyclohex-2-ene-1-carboxylate
• β-D-Glucopyranoside, 2-[[[[(1S)-1-hydroxy-6-oxo-2-cyclohexen-1-yl]carbonyl]oxy]methyl]phenyl, 2-benzoate

Tremulacin

CAS: 29836-40-6

Formula: C₂₇H₂₈O₁₁

Molecular weight: 528.51

Ref: 4Z-S-114004

Tremulacin

CAS: 29836-40-6

Natural glycoside

Formula: C₂₇H₂₈O₁₁

Purity: ≥ 90.0 % (HPLC)

Color and Shape: Powder

Molecular weight: 528.5

Ref: 5G-86065

Tremulacin

CAS: 29836-40-6

Tremulacin is a topical analgesic, which is derived from the bark of the white willow tree, Salix alba. This source is rich in salicylates, a group of compounds closely related to the active ingredients found in aspirin, known for their potent anti-inflammatory and pain-relieving properties. The mode of action of Tremulacin involves the inhibition of cyclooxygenase enzymes (COX-1 and COX-2), similar to non-steroidal anti-inflammatory drugs (NSAIDs). This leads to a decrease in the production of pro-inflammatory prostaglandins, thereby reducing inflammation and providing pain relief.

Formula: C₂₇H₂₈O₁₁

Purity: (Hplc-Ms) Min. 95 Area-%

Color and Shape: White Off-White Powder

Molecular weight: 528.5 g/mol

Ref: 3D-FT137854

Tremulacin

Controlled Product

CAS: 29836-40-6

Applications Tremulacin is used in the methods for treatment of adenoid cystic carcinoma using retinoic acid receptor agonists.
References Zon, L. I., et al.: PCT Int. Appl. 113pp. (2018)

Formula: C₂₇H₂₈O₁₁

Color and Shape: Neat

Molecular weight: 528.505

Ref: TR-T146820