CAS 298708-81-3

Methyl (4R)-4-(2-chloro-4-fluorophenyl)-2-(3,5-difluoro-2-pyridinyl)-1,4-dihydro-6-methyl-5-pyrimidinecarboxylate

Description:

Methyl (4R)-4-(2-chloro-4-fluorophenyl)-2-(3,5-difluoro-2-pyridinyl)-1,4-dihydro-6-methyl-5-pyrimidinecarboxylate, identified by its CAS number 298708-81-3, is a synthetic organic compound characterized by its complex molecular structure, which includes a pyrimidine ring and various halogenated aromatic substituents. This compound typically exhibits properties such as moderate solubility in organic solvents and potential bioactivity, making it of interest in pharmaceutical research. The presence of fluorine and chlorine atoms suggests enhanced lipophilicity and may influence its interaction with biological targets. The chirality at the 4R position indicates that the compound can exist in enantiomeric forms, which may have different biological activities. Its molecular framework suggests potential applications in medicinal chemistry, particularly in the development of therapeutic agents. As with many synthetic compounds, safety and handling precautions are essential, and its stability under various conditions should be evaluated in practical applications.

Formula: C₁₈H₁₃ClF₃N₃O₂

InChI: InChI=1S/C18H13ClF3N3O2/c1-8-14(18(26)27-2)15(11-4-3-9(20)5-12(11)19)25-17(24-8)16-13(22)6-10(21)7-23-16/h3-7,15H,1-2H3,(H,24,25)/t15-/m0/s1

InChI key: InChIKey=FVNJBPMQWSIGJK-HNNXBMFYSA-N

SMILES: C(OC)(=O)C=1[C@@H](NC(=NC1C)C2=C(F)C=C(F)C=N2)C3=C(Cl)C=C(F)C=C3

Synonyms:

• 5-Pyrimidinecarboxylic acid, 4-(2-chloro-4-fluorophenyl)-2-(3,5-difluoro-2-pyridinyl)-1,4-dihydro-6-methyl-, methyl ester, (4R)-
• Bay-41-4109
• Bayer 41-4109
• Methyl (4R)-4-(2-chloro-4-fluorophenyl)-2-(3,5-difluoro-2-pyridinyl)-1,4-dihydro-6-methyl-5-pyrimidinecarboxylate
• methyl (R)-4-(2-chloro-4-fluorophenyl)-2-(3,5-difluoropyridin-2-yl)-6-methyl-1,4-dihydropyrimidine-5-carboxylate
• BAY41-4109; BAY-41-4109; BAYER 41-4109

Bay 41-4109

CAS: 298708-81-3

Bay 41-4109 is a synthetic small molecule, which is a potent activator of soluble guanylate cyclase (sGC), derived from rational chemical design targeting specific signaling pathways. This compound primarily functions by binding to and stabilizing sGC in cells, enhancing the enzymatic conversion of GTP to cGMP, thereby modulating downstream signaling processes. Its mode of action facilitates the modulation of nitric oxide-mediated pathways, which are crucial in a variety of physiological processes.

Formula: C₁₈H₁₃ClF₃N₃O₂

Purity: Min. 95%

Molecular weight: 395.76 g/mol

Ref: 3D-YLA70881

Bay 41-4109

CAS: 298708-81-3

BAY 41-4109 is a potent inhibitor of human hepatitis B virus (HBV)(IC50 : 53 nM).

Formula: C₁₈H₁₃ClF₃N₃O₂

Color and Shape: Solid

Molecular weight: 395.76

Ref: TM-T10480L