CAS 2988804-46-0

3-tert-butyl-N-[(1R)-1-{4-[6-({5-[(2S)-4-{2-[4-(2,4-dioxo-1,3 -diazinan-1 -yl)phenyl] ethyl } -2-methylpiperazin-1 -yl]pyridin-2-yl}amino)pyrimidin-4-yl]-2-methylphenyl} ethyl] -1,2,4-oxadiazole-5 -ca

Description:

3-tert-butyl-N-[(1R)-1-{4-[6-({5-[(2S)-4-{2-[4-(2,4-dioxo-1,3-diazinan-1-yl)phenyl]ethyl}-2-methylpiperazin-1-yl]pyridin-2-yl}amino)pyrimidin-4-yl]-2-methylphenyl}ethyl]-1,2,4-oxadiazole-5-carboxamide is a complex organic compound characterized by its intricate molecular structure, which includes multiple functional groups such as an oxadiazole ring and various aromatic systems. This compound likely exhibits significant biological activity due to its diverse structural components, which may interact with biological targets. The presence of a tert-butyl group suggests enhanced lipophilicity, potentially influencing its pharmacokinetic properties. Additionally, the compound's multiple chiral centers indicate that it may exist in different stereoisomeric forms, which can affect its biological efficacy and safety profile. The CAS number 2988804-46-0 serves as a unique identifier for this substance, facilitating its identification in chemical databases and literature. Overall, this compound's complexity and functional diversity make it a subject of interest in medicinal chemistry and drug development.

Synonyms:

• 3-tert-butyl-N-[(1R)-1-{4-[6-({5-[(2S)-4-{2-[4-(2,4-dioxo-1,3 -diazinan-1 -yl)phenyl] ethyl } -2-methylpiperazin-1 -yl]pyridin-2-yl}amino)pyrimidin-4-yl]-2-methylphenyl} ethyl] -1,2,4-oxadiazole-5 -ca

PROTAC BTK Degrader-10

CAS: 2988804-46-0

PROTAC BTK Degrader-10 (Example 1P) is a PROTAC compound that targets BTK for degradation. It is applicable in the research of chronic lymphocytic leukemia (CLL). [Pink: ligand for target protein; Black: linker; Blue: ligand for E3 ligase Cereblon].

Formula: C₄₂H₄₉N₁₁O₄

Color and Shape: Solid

Molecular weight: 771.91

Ref: TM-T204382