CAS 2991-42-6

4-(trifluoromethyl)benzene sulfonyl chloride

Description:

4-(Trifluoromethyl)benzene sulfonyl chloride, also known as trifluoromethylbenzenesulfonyl chloride, is an organic compound characterized by the presence of a sulfonyl chloride functional group attached to a benzene ring that has a trifluoromethyl substituent. This compound typically appears as a colorless to pale yellow liquid or solid, depending on temperature and purity. It is known for its strong electrophilic nature due to the sulfonyl chloride group, making it a useful reagent in organic synthesis, particularly for the introduction of sulfonyl groups into various substrates. The trifluoromethyl group enhances the compound's lipophilicity and can influence the reactivity and stability of the resulting products. 4-(Trifluoromethyl)benzene sulfonyl chloride is generally handled with care due to its corrosive properties and potential to release toxic gases upon reaction with water or moisture. It is commonly used in the synthesis of pharmaceuticals, agrochemicals, and other fine chemicals, where it serves as an important building block in the development of sulfonamide derivatives and other functionalized compounds.

Formula: C₇H₄ClF₃O₂S

InChI: InChI=1S/C7H4ClF3O2S/c8-14(12,13)6-3-1-5(2-4-6)7(9,10)11/h1-4H

InChI key: InChIKey=OZDCZHDOIBUGAJ-UHFFFAOYSA-N

SMILES: C(F)(F)(F)C1=CC=C(S(Cl)(=O)=O)C=C1

Synonyms:

• 4-(Trifluoromethyl)Benzene-1-Sulfonyl Chloride
• 4-(Trifluoromethyl)benzenesulfonyl Chloride
• 4-(Trifluoromethyl)benzenesulphonyl chloride
• Benzenesulfonyl chloride, 4-(trifluoromethyl)-
• [4-(Trifluoromethyl)phenyl]sulfonyl chloride
• [p-(Trifluoromethyl)phenyl]sulfonyl chloride
• p-Toluenesulfonyl chloride, α,α,α-trifluoro-
• p-Trifluoromethylbenzenesulfonyl chloride
• α,α,α-Trifluoro-p-toluenesulfonyl chloride
• 4-(TRIFLUOROMETHYL)BENZENESULFONYCHLORIDE
• ALPHA,ALPHA,ALPHA-TRIFLUOROTOLUENE-4-SULFONYL CHLORIDE
• 4-(TRIFLUOROMETHYL)BENZENESULFONYL CHLORIDE 98%
• P-(TRIFLUOROMETHYL)BENZENESULFONYL CHLORIDE
• 4-(Trifluoromethyl)benzenesulphonyl chloride 98%
• BUTTPARK 52\11-36

4-(Trifluoromethyl)benzenesulfonyl Chloride

CAS: 2991-42-6

Formula: C₇H₄ClF₃O₂S

Purity: >98.0%(GC)(T)

Color and Shape: White or Colorles to Yellow to Orange powder to lump to clear liquid

Molecular weight: 244.61

Ref: 3B-T1795

4-(Trifluoromethyl)benzenesulfonyl chloride, 98%

CAS: 2991-42-6

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₇H₄ClF₃O₂S

Purity: 98%

Color and Shape: White to pale yellow or pale cream, Crystals or powder or crystalline powder or fused/lumpy solid

Molecular weight: 244.62

Ref: 02-A12907

4-(trifluoromethyl)benzenesulfonyl chloride

CAS: 2991-42-6

Formula: C₇H₄ClF₃O₂S

Purity: 96%

Color and Shape: Liquid

Molecular weight: 244.6187

Ref: IN-DA003KBK

4-(Trifluoromethyl)benzenesulphonyl chloride

CAS: 2991-42-6

4-(Trifluoromethyl)benzenesulphonyl chloride

Formula: C₇H₄ClF₃O₂S

Purity: 98%

Color and Shape: light yellow fused/ light yellow liquid fused solid

Molecular weight: 244.62g/mol

Ref: 54-PC7510

4-(Trifluoromethyl)benzenesulfonyl chloride

CAS: 2991-42-6

Formula: C₇H₄ClF₃O₂S

Purity: 96%

Color and Shape: Solid, Low Melting Solid

Molecular weight: 244.61

Ref: 10-F007589

4-Trifluoromethylbenzene sulfonyl chloride

CAS: 2991-42-6

4-Trifluoromethylbenzene sulfonyl chloride (TFB) is a functional group that is used as a ligand in some chemical reactions. TFB has been shown to be fluorescent, and can be used as a cancer cell marker. It also inhibits the growth of cancer cells by binding to their surface and inhibiting protein synthesis. 4-Trifluoromethylbenzene sulfonyl chloride can be synthesized by reacting ethylene with salicylic acid, followed by the reaction of the resulting ester with chloroform. This process yields TFB and chloride ions, which are then neutralized with sodium hydroxide to yield TFB sulfonate salt.

Formula: C₇H₄ClF₃O₂S

Purity: Min. 95%

Color and Shape: Colourless Or White To Light (Or Pale) Yellow To Brown Solid

Molecular weight: 244.62 g/mol

Ref: 3D-FT10629