CAS 29913-85-7

(3R,4aS,6R)-3,4,4a,5,6,7-Hexahydro-6,8-dihydroxy-3-methyl-1H-2-benzopyran-1-one

Description:

The chemical substance known as (3R,4aS,6R)-3,4,4a,5,6,7-Hexahydro-6,8-dihydroxy-3-methyl-1H-2-benzopyran-1-one, with the CAS number 29913-85-7, is a naturally occurring compound that belongs to the class of flavonoids. This compound features a complex bicyclic structure characterized by a benzopyran moiety, which is typical of many flavonoids. Its stereochemistry is defined by specific configurations at several chiral centers, contributing to its biological activity and interaction with various biological systems. The presence of hydroxyl groups at the 6 and 8 positions enhances its potential antioxidant properties, making it of interest in pharmacological research. Additionally, the methyl group at the 3 position may influence its solubility and reactivity. This compound is often studied for its potential health benefits, including anti-inflammatory and neuroprotective effects, and may be found in various plant sources. Its unique structural features and biological activities make it a subject of interest in both natural product chemistry and medicinal research.

Formula: C₁₀H₁₄O₄

InChI: InChI=1S/C10H14O4/c1-5-2-6-3-7(11)4-8(12)9(6)10(13)14-5/h5-7,11-12H,2-4H2,1H3/t5-,6-,7-/m1/s1

InChI key: InChIKey=VXOJVQJURAQQOK-FSDSQADBSA-N

SMILES: OC1=C2[C@](C[C@@H](C)OC2=O)(C[C@@H](O)C1)[H]

Synonyms:

• 1H-2-Benzopyran-1-one, 3,4,4a,5,6,7-hexahydro-6,8-dihydroxy-3-methyl-, [3R-(3α,4aβ,6β)]-
• 1H-2-Benzopyran-1-one, 3,4,4a,5,6,7-hexahydro-6,8-dihydroxy-3-methyl-, (3R,4aS,6R)-
• Isocoumarin, 3,4,4aα,5,6,7-hexahydro-6α,8-dihydroxy-3β-methyl-
• (3R,4aS,6R)-3,4,4a,5,6,7-Hexahydro-6,8-dihydroxy-3-methyl-1H-2-benzopyran-1-one
• 6-Hydroxyramulosin

6-Hydroxy ramulosin

CAS: 29913-85-7

6-Hydroxy ramulosin is a potent kinase inhibitor that has shown promising anticancer activity in both preclinical and clinical studies. This compound has been found to inhibit the activity of multiple kinases involved in cancer progression, including those responsible for cell proliferation, survival, and angiogenesis. Additionally, 6-Hydroxy ramulosin has been shown to induce apoptosis in cancer cells by disrupting key signaling pathways involved in tumor growth. This compound is derived from Chinese medicinal plants and has been found in human urine samples, indicating its potential as a natural anticancer agent. With its potent inhibitory effects on kinases and ability to induce apoptosis in cancer cells, 6-Hydroxy ramulosin holds great promise as a novel therapeutic for the treatment of various types of cancer.

Formula: C₁₀H₁₄O₄

Purity: Min. 95%

Molecular weight: 198.22 g/mol

Ref: 3D-EBA91385