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CAS 2991588-80-6

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  • GDCNF-11
    Targetmol
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    GDCNF-11

    CAS:
    <p>GDCNF-11, an HSP90-based HIM-PROTACGPX4 degrader, facilitates the ubiquitination and degradation of GPX4 through the HSP90 chaperone complex. This reduction in endogenous GPX4 induces ferroptosis in HT-1080 cells, with a DC50 value of 0.08 μM.</p>
    Formula:C48H53Cl2N13O5S
    Color and Shape:Solid
    Molecular weight:994.99

    Ref: TM-T200693