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CAS 2992670-33-2

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Found 1 products.
  • PROTAC EGFR degrader 9

    CAS:
    <p>PROTACEGFRdegrader 9 (Compound C6) is an orally active, CRBN-based PROTAC EGFR degrader. It has a DC50 of 10.2 nM and a Kd of 240.2 nM against EGFRL858R/T790M/C797S. PROTACEGFRdegrader 9 demonstrates effective degradation activity against various EGFR mutants while not affecting EGFRWT.</p>
    Formula:C45H48F3N9O6S
    Molecular weight:899.98